Results 91 to 100 of about 1,013,154 (317)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Mathematics Teaching in Brazil: Overview, Current Context, and Challenges
REDIMATThe article provides an overview of mathematics teaching in Brazil, examining various scenarios throughout the country’s history, guided by the question: What are the main historical milestones of mathematics teaching in Brazil and the intersections ...
Adriana Richit +1 more
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Cogent EducationCommunity participation is adopted as a strategy potential for enhancing infrastructure and facility adequacy in schools. However, many schools are still facing inadequacies.
Ahadi Mzumbwe Anania
doaj +1 more source
Basic education: challenges for post-pandemic Ecuadorian education
Revista MENDIVE, 2023 After the pandemic and the changes that it produced in education, a series of challenges are emerging for what education is going through. The objective of the article was aimed at analyzing the implemented innovations in education in the post-pandemic ...
Marco Vinicio Duque-Romero +1 more
doaj
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Bangladesh : Education Sector Review, Volume 1
, 2000 This Education Sector Review covers many major educational topics in Bangladesh. Six actions are needed to realize Bangladesh's vision in 2020: build a stronger, wider and deeper foundation of basic education;
World Bank
core +1 more source
Editorial: Higher education and non-cognitive skill development: Why, what and how?
Frontiers in Psychology, 2022 Paula Alvarez-Huerta +3 more
doaj +1 more source
Fineduca, 2022 This paper aims to discuss controversies around the new Fundeb, which was approved in August 2020 through Constitutional Amendment No. 108. It is assumed that the origin of the policy of funds in education and of Fundeb itself goes back to the disputes ...
Francisco José da Silva
doaj
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source