Results 141 to 150 of about 1,013,154 (317)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub   +24 more
wiley   +1 more source

A Simple and Effective Second-Order Numerical Algorithm for Tempered Fractional Differential Equation With Time Caputo-Tempered Fractional Derivative

open access: yesAdvances in Mathematical Physics
This paper presents an efficient numerical scheme for the space–time tempered fractional convection–diffusion equation, where the time derivative is the Caputo-tempered fractional derivative and the space derivatives are the normalized left and right ...
Dechao Gao   +3 more
doaj   +1 more source

Basic Education in the Netherlands [PDF]

open access: yes, 2008
Basic Education in the ...
openaire  

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

1968-1970 Adult Basic Education - Mississippi Module

open access: yes, 1968
1968 to 1970 Adult Basic Education teaching program Mississippi ...
Appalachian Adult Education Center
core  

Material Engagement Shaping Participation of Children on the Autism Spectrum: Embodiment and Subjectivity in Small-Group Learning

open access: yesEurope's Journal of Psychology
This study investigated the material engagement and their affordances for participation of children on the autism spectrum (AS) in small-group learning. Framed by a methodology called Idea Diary that fosters social interactions in classroom environments,
Juliene Madureira Ferreira   +1 more
doaj   +1 more source

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