Results 91 to 100 of about 10,190,253 (392)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

The Roman Shelter

open access: yesAnd, 2021
Isolamento e iperconnessione definiscono il campo di analisi in cui indagare l’idea di rifugio come casa. Il nostro modo di abitare è globalmente cambiato.
Orazio Carpenzano, Alfonso Giancotti
doaj  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Needs, equality and justice. Building an egalitarian proposal on basic needs [PDF]

open access: yes, 2011
Las necesidades han sido y continúan siendo un tema recurrente tanto en la filosofía del derecho como en la filosofía política, y en las ciencias sociales en general, aunque se han tratado la mayoría de las veces de manera inadecuada, de forma poco ...
Ribotta, Silvina
core   +1 more source

Theoretical surgery: a new specialty in operative medicine [PDF]

open access: yes, 1989
Theoretical surgery is defined as a nonoperative decision analysis and clinical and basic research supporting system for surgery. It developed to meet the needs of academic surgeons to coordinate communication with basic science disciplines. This article
Lorenz, Wilfried, Rothmund, M.
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Development and validation of the couple’s basic needs assessment scale

open access: yesمجله علوم روانشناختی, 2019
Background: The focus of reality therapy interventions in working with couples, is to raise couple’s awareness of their needs and to help them meet each other’s needs.
mona maaref   +3 more
doaj  

Maslow, Basic Needs and Contemporary Teacher Training Issues

open access: yesArchives of Current Research International, 2018
The work of Abraham Maslow and his hierarchy of needs has been referred to for decades. However, his ideas and concepts regarding basic needs still require review and reflection in this current zeitgeist. This paper reviews some of the issues confronting
M. Shaughnessy   +2 more
semanticscholar   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

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