Results 131 to 140 of about 4,712,528 (307)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

COVID-19 disproportionately impacts access to basic needs among households with disabled members. [PDF]

Disabil Health J, 2023
Streuli S, Garfein RS, Gaines T, Fielding-Miller R.   +3 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

MAIN CAREGIVER’S EXPERIENCE IN MEETING SELF-CARE NEEDS AMONG ADOLESCENTS WITH ASD IN PONTIANAK MUNICIPALITY, WEST BORNEO, INDONESIA: A QUALITATIVE STUDY

Belitung Nursing Journal, 2017
Background: Autism spectrum disorder (ASD) is a complex developmental disorder, increasing in number, faster than that of other developmental disorders in the world. This complex disorder affects a child’s self-autonomy, which is important for individual
Lilis Lestari, Elisabeth. S. Herini, Indria Laksmi Gamayanti   +2 more
doaj  

Sleep, Stress, and Cardiometabolic Health in Women of Childbearing Age with Overweight and Obesity

Women's Health Reports
Background: Sleep is important for health, but its relationship to cardiometabolic health in women of childbearing age remains unclear. Furthermore, stress, unmet basic needs, and lack of physical activity may be related to disrupted sleep and poor ...
Sarah S. Farabi, Cindy Schwarz, Alicia Persaud, Amanda Gilbert, Debra Haire-Joshu, Rachel G. Tabak   +5 more
doaj   +1 more source

Law Enforcement Officers' Ability to Recognize Emotions: The Role of Personality Traits and Basic Needs' Satisfaction. [PDF]

Behav Sci (Basel), 2022
Dirzyte A, Antanaitis F, Patapas A.
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Adaptive Complexity: Examining Texas Public Postsecondary Institutions’ Provision of Student Basic Needs Programs

Trends in Higher Education
This study reveals that the likelihood and diversity of postsecondary institutions providing basic needs programs are significantly influenced by institutional factors such as the institutions’ organization and size.
Lisa K. Zottarelli, Xiaohe Xu, Jayla M. Hatcher, Raji Thiruppathiraj, Natasha Ellis, Shamatanni Chowdhury, Thankam Sunil   +6 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Basic needs satisfaction in a military learning environment: An exploratory study. [PDF]

Mil Psychol, 2022
Lepinoy A, Lo Bue S, Vanderlinde R.
europepmc   +1 more source