Results 171 to 180 of about 10,190,253 (392)

Working Paper 68 - Governance and Poverty Reduction in Africa [PDF]

open access: yes
Of the 4 billion people that are known to be poor in the world today, Africa hasmore than her fair share, and the number of the poor, as percentage of the totalAfrican population, has been steadily increasing since independence.
Anyang' Nyong'o
core  

COVID-19 disproportionately impacts access to basic needs among households with disabled members. [PDF]

open access: yesDisabil Health J, 2023
Streuli S   +3 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

The Canadian Elder Standard - Pricing the Cost of Basic Needs for the Canadian Elderly [PDF]

open access: yes
We determined the after-tax income required to fi nance basic needs for Canadian elders living with different circumstances in terms of age, gender, city of residence, household size, homeowner or renter status, means of transportation, and health status.
Bonnie-Jeanne MacDonald   +2 more
core  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

The Role of Health, Religiosity, and Motivational Needs in Predicting Psychological Well-Being Among University of the Third Age Students

open access: yesReligions
Modern Western societies are “aging” at a very high rate, and more and more people require assistance and care. Old age has different faces, which is due to genetic conditions, as well as the different contexts and lifestyles of people.
Ewa Gurba   +2 more
doaj   +1 more source

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