Results 51 to 60 of about 4,712,528 (307)

Liberal Development Strategies: An Islamic Perspective

JISR Management and Social Sciences & Economics, 2009
State and policy vacuum is an unimaginable combination. State is anyhow concerned with policy making one way or another, even if it pretends to take the form of minimum or non-government intervention in the private businesses of the individuals because ...
Muhammad Zahid Siddique
doaj   +1 more source

Developing Students’ Intrinsic Interest in Reading Challenging Articles: An Application of Basic Psychological Need Supports

Sukma: Jurnal Pendidikan, 2022
Intrinsic motivation in doing academic tasks were important psychological aspects for improvement of students’ learning. However, intrinsic motivation in reading research articles was observably low among Cambodian undergraduate students.
Fidelis Chosa Kastuhandani, Sambo Ke
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Water for Survival, Water for Pleasure – A Biopolitical Perspective on the Social Sustainability of the Basic Water Agenda

Water Alternatives, 2017
This article explores the social sustainability of the basic water agenda. It does so through a biopolitical analysis of water narratives from eThekwini municipality, South Africa, where a policy of Free Basic Water (FBW) has been implemented.
Sofie Hellberg
doaj  

Devastating Flood in Nepal Amid a Humanitarian Crisis: A Call for Action

Journal of Nepal Medical Association
Floods have been a major problem in Nepal for a long time. Many lives have been lost due to the flood and people are still suffering from its effect. People are homeless and facing basic problems like food, and shelter.
Bibek Giri, Minal Jehan, Mubashir Mohiuddin, Ahmad Noor, Ahmed Sheraz   +4 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Escala de Percepción de Promoción del Bienestar para Entrenadores (EPPBE): Análisis inicial de sus propiedades psicométricas y validez. (Perception of Well-being Promotion for Coaches’ Scale (EPPBE): Initial analysis of psychometrics properties and validity).

Revista Internacional de Ciencias del Deporte, 2011
ResumenEste estudio analizó las propiedades psicométricas de la Escala de Percepción de Promoción del Bienestar para Entrenadores (EPPBE), compuesta por 6 dimensiones: Autocontrol, castigo, apoyo social, apoyo a la autonomía, apoyo a la competencia y ...
José Francisco Guzmán, Ángel García Ferriol   +1 more
doaj  

Measuring the satisfaction of a person’s basic need for security: Methodology development [PDF]

Известия Саратовского университета. Новая серия: Акмеология образования. Психология развития
The relevance of the study is due to the lack of a methodology to measure the satisfaction of a person’s need for security as one of the basic psychological needs.
Akbutaev, Vladimir O.
doaj   +1 more source