Results 131 to 140 of about 1,552,390 (331)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Systematic evaluation of the population-level effects of alternative treatment strategies on the basic reproduction number

open access: yes, 2018
An approach to estimate the influence of the treatment-type controls on the basic reproduction number, R 0 , is proposed and elaborated. The presented approach allows one to estimate the effect of a given treatment strategy or to compare a number of ...
Bulla, Ingo   +2 more
core  

A Dynamical Analysis on a Tumour Virotherapy Model with Standard Incident Rate [PDF]

open access: yes, 2017
This paper discusses a dynamical analysis on a model that governs the growth of tumour cell under a therapy by using oncolytic viruses, on the standard incident rate.
Ikawati, D. S. (Deasy)   +2 more
core  

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

Basic reproduction number and predicted trends of coronavirus disease 2019 epidemic in the mainland of China

open access: yesInfectious Diseases of Poverty, 2020
Background Coronavirus disease 2019 (COVID-19) has caused a serious epidemic around the world, but it has been effectively controlled in the mainland of China. The Chinese government limited the migration of people almost from all walks of life.
Yong Li   +3 more
semanticscholar   +1 more source

Altered Dynamic Functional Network Connectivity in Post‐Stroke Aphasia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Previous studies examining post‐stroke aphasia (PSA) patients via resting‐state functional magnetic resonance imaging (rs‐fMRI) have predominantly focused on static functional connectivity. In contrast, the current investigation aims to elucidate the alterations in dynamic functional network connectivity (dFNC) among PSA patients ...
Guihua Xu   +6 more
wiley   +1 more source

The role of asymptomatic carriers on the dynamics of a lymphatic filariasis model incorporating control strategies

open access: yesResults in Control and Optimization
This study presents a mathematical model to investigate the patterns of transmission in lymphatic filariasis. The model considers chronic, acute, and asymptomatic individuals and integrates key control strategies.
Mussa A. Stephano   +2 more
doaj   +1 more source

Estimation of Basic Reproduction Number (Ro) of Novel Coronavirus (COVID-19) from SEIR Model in Perspective of Bangladesh

open access: yes, 2020
Objective: The novel corona virus 19 (nCoV-19) created a global pandemic situation. To control this pandemic effectively, the basic reproduction number (Ro) is an effective epidemic tool.
T. Himel   +4 more
semanticscholar   +1 more source

Plasma Proteomic Signatures for Alzheimer's Disease: Comparable Accuracy to ATN Biomarkers and Cross‐Platform Validation

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu   +9 more
wiley   +1 more source

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