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Bridging basic science and clinical practice in orthopaedic translational research. [PDF]
J Orthop TranslatQi Q, Qin L.
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The Basic Science of Cannabinoids
Anesthesia & Analgesia, 2023The cannabis plant has been used for centuries to manage the symptoms of various ailments including pain. Hundreds of chemical compounds have been identified and isolated from the plant and elicit a variety of physiological responses by binding to specific receptors and interacting with numerous other proteins.
Alexandra, Sideris +2 more
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Clinical Orthopaedics and Related Research, 2001
Since the recognition of aseptic loosening by Charnley in the early 1960s, much information has been gained on the basic science of periprosthetic bone loss. Initially termed cement disease, it now generally is accepted that, in most instances, osteolysis is a manifestation of an adverse cellular response to phagocytosable particulate wear and ...
J J, Jacobs +4 more
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Since the recognition of aseptic loosening by Charnley in the early 1960s, much information has been gained on the basic science of periprosthetic bone loss. Initially termed cement disease, it now generally is accepted that, in most instances, osteolysis is a manifestation of an adverse cellular response to phagocytosable particulate wear and ...
J J, Jacobs +4 more
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Journal of Bone and Joint Surgery, 2006
The origin of the theory that the transmission of pain is through a single channel from the skin to the brain can be traced to the philosopher and scientist René Descartes. This simplified scheme of the reflex was the beginning of the development of the modern doctrine of reflexes.
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The origin of the theory that the transmission of pain is through a single channel from the skin to the brain can be traced to the philosopher and scientist René Descartes. This simplified scheme of the reflex was the beginning of the development of the modern doctrine of reflexes.
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BASIC SCIENCE, SCIENCE, AND MEDICAL EDUCATION
Lancet, The, 1976It is generally accepted that medical students should learn those stories from the basic sciences which enable medicine to be rational. But there are several reasons why science as an explanatory activity has much more to offer, particularly if the views of Popper are accepted. Unfortunately an appreciation of the nature of science is only accidentally
E J Campbell
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Perspectives in Biology and Medicine, 2010
After almost 50 years in science, I believe that there is an acceptable, often advantageous chasm between open-ended basic research—free exploration without a practical destination and in which the original ideas may fade into new concepts—and translational research or clinical research. My basic research on crystalline (proteins conferring the optical
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After almost 50 years in science, I believe that there is an acceptable, often advantageous chasm between open-ended basic research—free exploration without a practical destination and in which the original ideas may fade into new concepts—and translational research or clinical research. My basic research on crystalline (proteins conferring the optical
openaire +2 more sources