Results 151 to 160 of about 27,246 (267)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Perivascular spaces and basilar artery remodeling in Fabry disease-a dual vascular pathology. [PDF]

Front Neurol
Roh J, Cheon CK, Lee SY, Baik SK, Park MG, Park KP, Ahn SH.   +6 more
europepmc   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Bridging therapy versus mechanical thrombectomy alone in patients with basilar artery occlusion and mild symptoms: a retrospective observational study. [PDF]

J Neurol
Bellavia S, Alexandre AM, Scarcia L, Frisullo G, Pedicelli A, Brunetti V, Gabrieli JD, Da Ros V, Caragliano AA, Buonomo O, Semeraro V, Ganimede MP, Salsano G, Mavilio N, Chausson N, Schwarz G, Cascio Rizzo A, Piano M, Caproni S, Abruzzese S, Lozupone E, Calabresi P, Broccolini A.   +22 more
europepmc   +1 more source

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Diagnostic Challenges in Acute Basilar Artery Occlusion Successfully Treated With Mechanical Thrombectomy: A Case Report. [PDF]

Cureus
Palacios AA, Valverde JW, Serrano Reyes JC, Jaen RL, Valdes JR.   +4 more
europepmc   +1 more source

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

Advanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang, Shaojie Chen, Chengzong Li, Hongyi Cheng, Jincheng Jiao, Xiafeng Peng, Yike Zhang, Wei Sun, Feng Zhang, Chang Cui, Minglong Chen   +10 more
wiley   +1 more source

Real-world effectiveness of thrombectomy for basilar artery occlusion: lessons beyond the ATTENTION and BAOCHE trials. [PDF]

Eur Stroke J
Lee JY, Park SH, Lee K, Lee SJ, Kang K, Cha JK, Guk HS, Kim N, Kim J, Kim DY, Kim JY, Kang J, Kim BJ, Han MK, Choi JK, Park TH, Kwon DH, Lee J, Park HK, Cho YJ, Hong KS, Choi S, Lee M, Oh MS, Yu KH, Lee BC, Kim H, Choi KH, Kim JT, Gwak DS, Kim DE, Kim JG, Choi JC, Yum KS, Shin DI, Kim WJ, Kwon JH, Park HJ, Hong JH, Sohn SI, Lee SH, Kim C, Park C, Jeong HB, Park KY, Han JH, Lee D, Park JM, Park BS, Lee KJ, Kim CK, Oh K, Woo HG, Heo SH, Lee J, Lee JS, Gorelick PB, Kim JG, Bae HJ.   +58 more
europepmc   +1 more source

Basilar Artery Stenosis and Thrombosis [PDF]

Proceedings of the Royal Society of Medicine, 1954
openaire   +2 more sources

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source