Results 151 to 160 of about 151,573 (268)

An examination of atlanto-occipital curvature in adult Chiari malformation type 1 and control groups. [PDF]

J Craniovertebr Junction Spine
Karamzadeh M, Al Samman MM, Labuda R, Bhadelia RA, Millard JA, Bishop PD, Allen PA, Fultz TJ, Raymond SB, Tsai JP, Hussain MS, Amini R, Loth F.   +12 more
europepmc   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Is atlantoaxial instability the cause of type 3 Klippel-Feil anomaly? Outcome analysis of 99 patients treated by atlantoaxial fixation: A case series. [PDF]

J Craniovertebr Junction Spine
Goel A, El-Ghandour NMF, Shah A, Prasad A, Doshi J, Gautam S, Vutha R, Vaja T.   +7 more
europepmc   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

When "Metastatic Disease" Is Not Metastatic: Diffuse Large B-cell Lymphoma Presenting With a Perisplenic Mass, Pulmonary Masses, Pleural Effusion, and Retroperitoneal Lymphadenopathy. [PDF]

Cureus
Furlan Silva Fabri R, Penoth Gomez L, Sirineni S, Balasubramanian A, Chennareddy V, Soliman M, Hakim N, Soskin B.   +7 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Atlanto-occipital assimilation: the role of ex-, basi-, and suboccipital bones in the physiopathology of type I basilar invagination. Patient series. [PDF]

J Neurosurg Case Lessons
Maciel TMM, Botelho RV.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Chiari malformation I and abducens nerve palsy: an overview of the documented cases. [PDF]

Ann Med Surg (Lond)
Atallah O, Sharshera MW, Awuah WA, Lavarone S, Ergen A, Chaurasia B.   +5 more
europepmc   +1 more source