The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Prediction of UGT-mediated phase II metabolism via ligand- and structure-based predictive models. [PDF]
Bono L +8 more
europepmc +1 more source
Ecosystem-based adaptation in cities: An analysis of European urban climate adaptation plans
Davide Geneletti, Linda Zardo
openalex +2 more sources
Taper-in-taper fiber structure-based LSPR sensor for alanine aminotransferase detection
Zhi Wang +5 more
openalex +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
How do I evaluate myself? The importance of examining overevaluation of muscularity in risk for eating disorder symptoms. [PDF]
White C, Maraun M, Zaitsoff S.
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Limitations of Linear Dimensional Reduction Methods in Chronic Obstructive Pulmonary Disease Phenotyping. [PDF]
Takefuji Y.
europepmc +1 more source
Affective EEG-Based Person Identification Using the Deep Learning Approach [PDF]
Theerawit Wilaiprasitporn +5 more
openalex +1 more source

