Results 201 to 210 of about 8,045,847 (325)

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Creating a Superiorly Based Pharyngeal Flap: Is Prominence of C1 Superior Enough, and Will Adenoid Pad Be in the Way? [PDF]

Plast Reconstr Surg Glob Open
Sitzman TJ, Chee-Williams JL, Snodgrass TD, Gilbert IR, Tollefson TT, Singh DJ, Perry JL.   +6 more
europepmc   +1 more source

THE THERMODYNAMIC RELATIONS OF THE OXYGENAND BASE-COMBINING PROPERTIES OF BLOOD

, 1924
William Stadie, Kirby A. Martin
openalex   +1 more source

REMARKS ON STANDARDS FOR NORMAL BASAL METABOLISM. [PDF]

, 1921
J. H. Means
openalex   +1 more source

From Eminence-Based to Error-Based to Evidence-Based Surgery [PDF]

Scandinavian Journal of Surgery, 2008
openaire   +3 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Outlines of Cosmic Philosophy, based on the Doctrine of Evolution, with Criticisms on the Positive Philosophy [PDF]

, 1875
Douglas A. Spalding
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Efficacy and safety of PD-1/PD-L1 inhibitors alone or in combination in the treatment of metastatic or advanced renal cell carcinoma: a network meta-analysis. [PDF]

Front Immunol
Zhang D, Shen C, Zhang W, Chen H, Zhao J.   +4 more
europepmc   +1 more source

A DEVELOPMENTAL ANALYSIS OF THE LETHAL MUTANT L(2)GL OF DROSOPHILA MELANOGASTER BASED ON CYTOPHOTOMETRIC DETERMINATION OF NUCLEAR DESOXYRIBONUCLEIC ACID (DNA) CONTENT [PDF]

, 1957
Robert M. Welch
openalex   +1 more source