Results 31 to 40 of about 40,700 (268)

Bridging the Loneliness Gap: Depression, Connectivity, and Isolation in Pediatric Oncology Patients and Their Peers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Loneliness is associated with adverse physical and mental health outcomes and remains understudied in children and adolescents undergoing cancer therapy. Pediatric oncology patients may be at increased risk due to medical isolation and disruption of social networks.
Charlotte N. Stahlfeld, Scott H. Maurer, Michelle D. Watkinson, John Nury, Elise Barberis, Molly C. Mack   +5 more
wiley   +1 more source

A fluorescent STING ligand sensor for high-throughput screening of compounds that can enhance tumor immunotherapy

Cell Reports: Methods
Summary: The activation of the stimulator of interferon genes (STING) pathway triggers the release of type I interferons that can potentiate the host immune response against tumors.
Pengkai Sun, Bin Wang, Caiyun Liu, Zixiong Wang, Yang Liu, Yuan-Biao Qiao, Xinjian Li   +6 more
doaj   +1 more source

NEW HISTORY BOOKS ABOUT CENTRAL BLACK EARTH

Вестник Тамбовского университета. Серия: Гуманитарные науки, 2017
Review on monograph by V.A. Pertsev “The Financial Situation of the Population of the RSFSR (the second half of 1950-1980s): Basing on the Materials of Central Black Earth Regions” (2013) and “Social Insurance and Services of the Population of the RSFSR (
V. V. Kanishchev
doaj   +1 more source

Early Body Mass Index z‐Score Change and Resolution of Severe Malnutrition in Children With Sickle Cell Anemia in a Low‐Income Setting: A Prospective Single‐Arm Extension Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo, Shehu Umar Abdullahi, Hassan Adam Murtala, Halima Kabir, Khadija A. Shamsu, Sari A. Acra, Virginia A. Stallings, Mark Rodeghier, Michael R. DeBaun, Lauren J. Klein   +9 more
wiley   +1 more source

Global, regional, and national burden of chronic kidney disease attributable to high fasting plasma glucose from 1990 to 2019: a systematic analysis from the global burden of disease study 2019

Frontiers in Endocrinology
PurposeGiven the rising prevalence of high fasting plasma glucose (HFPG) over the past three decades, it is crucial to assess its global, national, and regional impact on chronic kidney disease (CKD).
Huizhi Wei, Jinhong Ren, Rui Li, Xiaoming Qi, Fan Yang, Qingshan Li, Qingshan Li   +6 more
doaj   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Engineered Panax notoginseng polysaccharide micelles inhibit macrophage polarization and delay the progression of rheumatoid arthritis via JAK2-STAT3 signaling pathway

Journal of Nanobiotechnology
Background The imbalance of macrophage polarization plays a pivotal role in the progression of rheumatoid arthritis (RA). Reprogramming macrophages from the pro-inflammatory M1 phenotype to the anti-inflammatory M2 phenotype is considered a promising ...
Yang Yu, Liang Kong, Rui-bo Guo, Ya-ni Zhang, Shu-tong Li, Feng-yuan Zhang, Xin Wang, Yang Liu, Xiu-Ying Li, Xue-tao Li   +9 more
doaj   +1 more source

Evidence based and guideline based medicine [PDF]

Emergency Medicine Journal, 2000
Editor,—Evidence based and guideline based medicine is justifiably emphasised in current accident and emergency (A&E) medicine practice. At St James's University Hospital in Leeds, the A&E trainees participate in regular evidence based critical appraisal sessions as part of education development, and such skills are assessed in our Faculty of Accident ...
openaire   +2 more sources

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Diagnostics basing on testing paths: the method of patterns

Экспериментальная психология, 2018
Presented is the method of patterns to diagnose subjects basing on testing paths which represent results of completion of tasks in the order of their appearance.
L.S. Kuravsky, G.A. Yuryev, D.V. Ushakov, N.E. Yuryeva, E.A. Valueva, E.M. Lapteva   +5 more
doaj   +1 more source