Results 61 to 70 of about 34,952,696 (369)
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali+3 more
wiley +1 more source
Origin of the second coherent peak in the dynamical structure factor of an asymmetric spin-ladder
Appearance of the second coherent peak in the dynamical structure factor of an asymmetric spin ladder is suggested. The general arguments are confirmed by the first order (with respect to the asymmetry) calculation for a spin ladder with singlet-rung ...
M. Hagiwara+3 more
core +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
The Functions of Computer Assisted Language Learning in Formation of Linguistic and Communicative Competences [PDF]
This article deals with behavioristic, communicative, intergrative approaches towards computer assisted language learning in formation of linguistic and communicative competences basing on main functions of computer in the teaching process: a tutor, a ...
Калініна, С. С.
core
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Evidence‐based and patient‐based dermatology
Evidence‐based medicine is a cornerstone for dermatological treatments. Guidelines are based on systemic literature reviews; in particular, considering those publications on therapeutic interventio...
openaire +3 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
KIDS COUNT Indicator Brief: Increasing the Percentage of Children Living in Two-Parent Families [PDF]
Examines trends, by race/ethnicity, in the percentage of children with the economic and other benefits of two-parent families. Offers strategies to raise the percentage, such as basing policies on research linking economic security and family ...
Barbara Shore, Rima Shore
core
Penalizing Cartels: The Case for Basing Penalties on Price Overcharge
In this paper we set out the welfare economics based case for imposing cartel penalties on the cartel overcharge rather than on the more conventional bases of revenue or profits (illegal gains).
Y. Katsoulacos, E. Motchenkova, D. Ulph
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source