FEBS Open Bio, EarlyView.The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Comparative Assessment of Graglia-Wilton-Peterson and Rao-Wilton-Glisson Basis Functions for Radiofrequency Coil Modeling in Magnetic Resonance Imaging. [PDF]
IEEE J Multiscale Multiphys Comput TechFranzò D +4 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Multiresolution Quantum Chemistry: Nonlinear Response Properties at the Basis Set Limit. [PDF]
J Chem Theory ComputHurtado A, Sekino H, Harrison RJ.
europepmc +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
The ancient Iraqi philosophical thought is a base for Greek philosophy
آثار الرافدين, 2012 Shaalan Kamel Ismail
doaj +1 more source
Electrospun biodegradable polycaprolactone filter media for filtering facepiece respirators. [PDF]
J Mater Sci PolymEwell N +3 more
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
The Basis for Progress in Chemotherapy [PDF]
CA: A Cancer Journal for Clinicians, 1972 openaire +3 more sources
Jahn-Teller Distortions in Pseudo-Octahedral Low-Spin Ni(III) Complexes With O,O or N,N Bidentate Ligands: A DFT Study. [PDF]
J Comput ChemConradie J.
europepmc +1 more source