Results 71 to 80 of about 7,221,182 (312)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Interkulturelles Lernen Basis kommunaler Auslaenderarbeit
, 1995 UuStB Koeln(38)-950106658 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische ...
Friedrich-Ebert-Stiftung Forschungsinstitut Abt. Arbeits- und Sozialforschung, Bonn (Germany)
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Pengembangan Basis Data Atmosfer Indonesia
, 2014 Basis data atmosfer Indonesia merupakan sistem yang mengatur penyimpanan dan pengambilan data atmosfer Indonesia dan dibangun agar data dapat diakses dengan mudah dan cepat.
Edy Maryadi +3 more
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RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Rancangan Basis Data f0F2 Ionosfer
, 2012 Organisasi rancangan basis data foF2 adalah secara bertingkat dan berurut dari. interface. Sebagai studi kasus pada sistem basis data adalah penentuan lebar pita faktor desil foF2 Penggunaan basis data untuk pemrosesan data dikerjakan dengan merancang ...
Slamet Syamsudin
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Multi-element stochastic reduced basis methods [PDF]
, 2007 This paper presents mutli-element Stochastic Reduced Basis Methods (ME-SRBMs) for solving linear stochastic partial differential equations. In ME-SRBMs, the domain of definition of the random inputs is decomposed into smaller subdomains or random ...
Surya Mohan, P. +5 more
core +1 more source
A solvability conditions of mixed problems for equations of parabolic type with involution
Қарағанды университетінің хабаршысы. Математика сериясы, 2018 In this work the partial differential equations with involutions are considered. The mixed problems for the parabolic type equation, with constant and variable constants, corresponding to the Dirichlet type boundary conditions is investigated.
A.A. Sarsenbi
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source