Results 91 to 100 of about 6,738,298 (325)

Molecular basis of protein function [PDF]

Nature, 1979
Molecular Interactions and Activity in Proteins. (Ciba Foundation Symposium No. 60 (new series).) (Excerpta Medica: Amsterdam, Oxford and New York. 1979.) $28.50; Df164.
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An Embedded Neural Network Approach for Reinforcing Deep Learning: Advancing Hand Gesture Recognition [PDF]

Journal of Universal Computer Science
Deep neural networks (DNNs) can face limitations during training for recognition, motivating this study to improve recognition capabilities by optimizing deep learning features for hand gesture image recognition. We propose a novel approach that enhances
Anwar Mira, Olaf Hellwich
doaj   +3 more sources

Compound basis arising from the basic $A^{(1)}_{1}$-module

, 2008
A new basis for the polynomial ring of infinitely many variables is constructed which consists of products of Schur functions and Q-functions.
A. Lascoux, Hiro-Fumi Yamada, Hiroshi Mizukawa, I.G. Macdonald, J. Stembridge, K. Uno, Kazuya Aokage, S. Ariki, T. Ikeda, T. Ikeda, T. unya Nakajima, V.G. Kac, Y. Chen   +12 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Wavelet Analysis for Localization of Heterogeneities in Byte Distribution in a File to Searching for Encrypted Data

Безопасность информационных технологий, 2015
This article is focused on the choice of approach to localize a deviation in byte distribution in a file by means of the wavelet analysis. In the article the dependence of scale parameter and wavelet coefficients values is revealed.
Веста Сергеевна Матвеева, Alexandr Vladimirovich Mamaev   +1 more
doaj  

Application of Radial Basis Function Network for the Modeling and Simulation of Turbogenerator

Journal of Advances in Information Technology, 2013
In this paper, the applicability of Radial Basis Function (RBF) network for the modeling and simulation of turbogenerators is presented. It is expensive and time- consuming to do experimental work to predict the behaviour of Turbogenerators with changing
Mohsen Hayati, Abbas Rezaei, Leila Noori
doaj   +1 more source

Power quality disturbances classification using autoencoder and radial basis function neural network

, 2023
Venkataramana Veeramsetty, Aitha Dhanush, Aluri Nagapradyullatha, Gundapu Rama Krishna, Surender Reddy Salkuti   +4 more
openalex   +1 more source

Electron transport through an interacting region: The case of a nonorthogonal basis set

, 2005
The formula derived by Meir and Wingreen [Phys. Rev. Lett. {\bf 68}, 2512 (1992)] for the electron current through a confined, central region containing interactions is generalized to the case of a nonorthogonal basis set.
H. Bruus, H. Haug, Kristian S. Thygesen, R. A. Lippert, S. Datta, Y. Xue   +5 more
core   +1 more source