Results 111 to 120 of about 6,738,298 (325)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Decision Feedback Equalizers Using Radial Basis Function Networks

open access: yesJournal of King Saud University: Engineering Sciences, 2000
Decision feedback equalizers (DFE)s are used extensively in practical communication systems. They are more powerful than linear equalizers especially for severe inter-symbol interference (ISI) channels with deep frequency null.
S.A. Zummo, A. Balghonaim, M. Mohandes
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Automotive Industry Video-Commercials – A Pluralistic Research Based on an Eye-Tracking Experiment [PDF]

open access: yesJournal of Emerging Trends in Marketing and Management, 2019
Eye-tracking is an innovative way of finding where participants look in a video-commercial, at which car components from the automotive industry video-commercials and if they can express in words what they perceive with their eyes.
Cristiana Chiriac, Laura Daniela Roșca
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Peramalan Netflow Uang Kartal dengan Metode ARIMAX dan Radial Basis Function Network (Studi Kasus di Bank Indonesia) [PDF]

open access: yes, 2014
BI memiliki satu tujuan tunggal yakni mencapai dan menjaga kestabilan nilai rupiah. Salah satu hal yang dilakukan untuk memenuhi tujuan ini adalah dengan pemantauan netflow uang kartal dengan meramalkan netflow uang kartal. Penelitian ini bertujuan untuk
suhartono, S. (suhartono)   +1 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

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