Results 111 to 120 of about 1,380,984 (267)
[Toxicological basis for evaluating health risk].
The fundamental premises and toxicological methods used to evaluate exposure to chemicals in the environment have been discussed, with particular regard to the approach and methods for health risk assessment of carcinogens and non-carcinogens. The main disputable problems related to risk assessment and risk estimation have been listed.
R, Rolecki, T, Dutkiewicz, J, Kończalik
openaire +1 more source
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub +24 more
wiley +1 more source
Basis risk in solvency capital requirements for longevity risk
The international guidelines of Solvency II prescribe a regulation which should help insurance industry mitigating undesired outcomes arising from the exposure to the systemic risks. In particular, the rules on Solvency Capital Requirements recommend to separately compute them for each risk factor, where for the longevity risk sub-module the Solvency ...
COPPOLA, MARIAROSARIA, V. D'Amato
openaire +3 more sources
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Can index insurance keep up with climate change? Rethinking historical data models
Batsirai Mazviona, Simon Sølvsten
doaj +1 more source
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr +5 more
wiley +1 more source
Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham +29 more
wiley +1 more source
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie +3 more
wiley +1 more source
Proposal of a procedure to stratify the reidentification risk of medical data: RIMEDA. [PDF]
Behre S +3 more
europepmc +1 more source

