Results 21 to 30 of about 3,884 (191)

Moving instead of asking? performance-based tests and BASFI-questionnaire measure different aspects of physical function in ankylosing spondylitis [PDF]

, 2012
INTRODUCTION: Ankylosing Spondylitis (AS) is characterised by limitations in physical function. The Bath Ankylosing Spondylitis Functional Index (BASFI) is considered to be the gold-standard to assess physical function in AS patients.
Dekker, J., Denderen, J.C. van, Dijkmans, B.A.C., Horst-Bruinsma, I.E. van der, Leeden, M. van der, Nurmohamed, M.T., Steultjens, M.P., Weely, S.F.E. van   +7 more
core   +9 more sources

Determining factors related to impaired spinal and hip mobility in patients with axial spondyloarthritis: longitudinal results from the DESIR cohort

RMD Open, 2020
Objective To investigate the determinants of impaired spinal and hip mobility in patients with early axial spondyloarthritis (axSpA).Methods Five-year longitudinal data from the DEvenir des Spondyloarthrites Indifférenciées Récentes (DESIR) cohort were ...
Joao Fonseca, Pedro D Carvalho, Ana Marreiros   +2 more
doaj   +1 more source

Physical function and sex differences in radiographic axial spondyloarthritis: a cross-sectional analysis on Bath Ankylosing Spondylitis Functional Index

Arthritis Research & Therapy, 2023
Background Physical function is an important determinant of health-related quality of life in radiographic axial spondyloarthritis patients (r-axSpA).
Magnus Hallström, Eva Klingberg, Anna Deminger, Jeannette Beckman Rehnman, Mats Geijer, Helena Forsblad-d’Elia   +5 more
doaj   +1 more source

Tofacitinib Efficacy and Safety in Patients With Ankylosing Spondylitis by Prior Biologic Disease‐Modifying Antirheumatic Drug Use: A Post Hoc Analysis

ACR Open Rheumatology, Volume 5, Issue 12, Page 632-643, December 2023., 2023
Objective To evaluate the efficacy and safety of tofacitinib in patients with ankylosing spondylitis (AS) by prior biologic disease‐modifying antirheumatic drug (bDMARD) use. Methods Data from a placebo‐controlled, double‐blind study of patients with active AS were analyzed.
Atul Deodhar, Helena Marzo‐Ortega, Joseph Wu, Cunshan Wang, Oluwaseyi Dina, Keith S. Kanik, Lara Fallon, Lianne S. Gensler   +7 more
wiley   +1 more source

Decreased levels of T follicular helper (CD4+CXCR5+) cells and CD27+CD38+ and CD27+CD38− B cells in ankylosing spondylitis patients correlate with markers of inflammation

Scandinavian Journal of Immunology, Volume 97, Issue 1, January 2023., 2023
Abstract The purpose of this study was to study CD4+CXCR5+ T follicular helper (TFH) cells, CD27+CD38+ plasmablasts and CD27+CD38− memory B cells, as well as disease‐related factors in patients with ankylosing spondylitis (AS) from northern Sweden. Peripheral blood mononuclear cells (PBMC) from 50 patients with AS (mean age 52 ± 9 years, 66% men, 100 ...
Kristina Lejon, Urban Hellman, Anjani Kumar, Helena Forsblad‐d'Elia   +3 more
wiley   +1 more source

Safety and Efficacy of Bimekizumab in Patients With Active Ankylosing Spondylitis: Three‐Year Results From a Phase IIb Randomized Controlled Trial and Its Open‐Label Extension Study

Arthritis &Rheumatology, Volume 74, Issue 12, Page 1943-1958, December 2022., 2022
Objective To assess the long‐term safety, tolerability, and efficacy of bimekizumab in patients with active ankylosing spondylitis (AS). Methods Patients with active AS who completed the dose‐ranging, 48‐week BE AGILE randomized controlled trial were eligible to participate in an open‐label extension (OLE) study, in which patients received 160 mg of ...
Xenofon Baraliakos, Atul Deodhar, Maxime Dougados, Lianne S. Gensler, Anna Molto, Sofia Ramiro, Alan J. Kivitz, Denis Poddubnyy, Marga Oortgiesen, Thomas Vaux, Carmen Fleurinck, Julie Shepherd‐Smith, Christine de la Loge, Natasha de Peyrecave, Désirée van der Heijde   +14 more
wiley   +1 more source

Improvement of Function and Its Determinants in a Group of Axial Spondyloarthritis Patients Treated with TNF Inhibitors: A Real-Life Study

Rheumatology and Therapy, 2020
Introduction The aim of this work is to investigate the improvement of physical function and its determinants in axial spondyloarthritis (SpA) patients treated with tumor necrosis factor (TNF) inhibitors in a real clinical practice setting.
Ennio Lubrano, Fabio Massimo Perrotta, Maria Manara, Salvatore D’Angelo, Roberta Ramonda, Leonardo Punzi, Olga Addimanda, Carlo Salvarani, Antonio Marchesoni   +8 more
doaj   +1 more source

Disease and psychological status in ankylosing spondylitis. [PDF]

, 2006
Objectives. Psychological factors may be important in the assessment and management of ankylosing spondylitis (AS). Our primary objective was to describe associations between disease and psychological status in AS, using AS-specific assessment tools and ...
Goodacre, J. A., Goodacre, L., Grennan, D., Martindale, J., Smith, J., Sutton, Chris J   +5 more
core   +1 more source

Validity and feasibility of remote measurement systems for functional movement and posture assessments in people with axial spondylarthritis

Healthcare Technology Letters, Volume 9, Issue 6, Page 110-118, December 2022., 2022
This article introduced and evaluated the validity of a new artificial intelligence‐driven method of automatically analysing a range of standard clinical functional tests. Remote technology systems in rehabilitation have the potential to reduce health inequality and improve cost and time effectiveness for both patients and the health system.
Erin Hannink, Maedeh Mansoubi, Neil Cronin, Benjamin Wilkins, Ali A. Najafi, Benjamin Waller, Helen Dawes   +6 more
wiley   +1 more source

Clinical and MRI responses to etanercept in early non-radiographic axial spondyloarthritis : 48-week results from the EMBARK study [PDF]

, 2015
Objective: To evaluate the efficacy and safety of etanercept (ETN) after 48 weeks in patients with early active non-radiographic axial spondyloarthritis (nr-axSpA).
Bonin, Randi, Braun, Jürgen, Bukowski, Jack F, Citera, Gustavo, Dougados, Maxime, Jones, Heather, Kotak, Sameer, Logeart, Isabelle, Maksymowych, Walter P, Marshall, Lisa, Pedersen, Ron, Sieper, Joachim, Van den Bosch, Filip, van der Heijde, Désirée, Vlahos, Bonnie, Wajdula, Joseph   +15 more
core   +1 more source