Results 221 to 230 of about 2,280,434 (325)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, Volume 20, Issue 11, Page 2918-2935, November 2026.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Real-World Clinical Practice Evaluation of Tralokinumab in Atopic Dermatitis: A 52-Week Multi-Center Retrospective Study in the Basque Country. [PDF]

open access: yesJ Clin Med
Izu Belloso RM   +7 more
europepmc   +1 more source

Elasticity‐Driven Periodic Polarization Patterns in a Chiral Ferroelectric Nematic Fluid

open access: yesAdvanced Materials, Volume 38, Issue 62, 6 November 2026.
Chiral polar ferroelectric nematic fluids exhibit spontaneous formation of stripe, square, and hexagonal polarization textures under confinement. Controlled by thickness and anchoring, these patterns produce spatially modulated nonlinear optical responses.
Anej Sterle   +11 more
wiley   +1 more source

Strain and Chirality: Catalytic Asymmetric Synthesis of Planar Chiral [2.2]Paracyclophanes

open access: yesChemistryEurope, Volume 4, Issue 11, November 2026.
Catalytic asymmetric synthesis is transforming access to planar‐chiral [2.2]paracyclophanes. This Review highlights recent advances in catalytic desymmetrization and asymmetric functionalization, emphasizing how catalyst design and PCP geometry govern reactivity and stereocontrol.
Daniel Alonso   +2 more
wiley   +1 more source

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