Results 51 to 60 of about 802,447 (332)

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Shc depletion stimulates brown fat activity in vivo and in vitro. [PDF]

, 2014
Adipose tissue is an important metabolic organ that integrates a wide array of homeostatic processes and is crucial for whole-body insulin sensitivity and energy metabolism.
Bettaieb, Ahmed, Connell, Michelle, Cortopassi, Gino, Fong, Jennifer, Griffey, Stephen, Hagopian, Kevork, Haj, Fawaz, Kim, Kyoungmi, Lam, Adam, Ramsey, Jon, Rowland, Douglas, Sahdeo, Sunil, Tomilov, Alexey, Tomilova, Natalia   +13 more
core   +1 more source

A Hubble Space Telescope Imaging Survey of Low-redshift Swift-BAT Active Galaxies* [PDF]

, 2021
Minjin Kim, Aaron J. Barth, Luis C. Ho, Suyeon Son   +3 more
openalex   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Entrepreneurs' Access to Private Equity in China: The Role of Social Capital [PDF]

, 2002
Drawing on Social network theory, this article argues for enhancing effects of social capital of entrepreneurs on investment selection decisions of venture capitalists (to invest versus not to invest), and main effects of social capital on investment ...
Batjargal, Bat, Liu, Mannie M.
core   +2 more sources

Storage of Doppler-Shift Information in the Echolocation System of the "CF-FM"-Bat, Rhinolophus ferrumequinum [PDF]

, 1976
The greater horseshoe bat (Rhinolophus ferrumequinum) emits echolocation sounds consisting of a long constant-frequency (CF) component preceeded and followed by a short frequency-modulated (FM) component. When an echo returns with an upward Doppler-shift,
Schuller, Gerd, Suga, Nobuo
core   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Results of research on the bat fauna of the Vârghiş Gorge (Eastern Carpathians, Romania)

Travaux de l'Institut de Speologie Emile Racovitza, 2007
During the period between 2000 to 2004 in the Vârghiş Gorge (Eastern Carpathians, Romania) 23 caves were checked in order to collect chiropterological data. In 16 of them bats or bone materialwere found.
CSABA JÉRE, ANNAMÁRIA DÓCZY, LEVENTE BARTI   +2 more
doaj  

Needle size for thyroid fine needle aspiration cytology. A single institution experience

Frontiers in Surgery
BackgroundFine needle aspiration cytology (FNAC) is an invasive diagnostic technique which is widely used for the cytological diagnosis of thyroid nodules.
Pasquale Cianci, Rocco Tumolo, Ivana Conversano, Damiano Travaglia, Giuseppe Trigiante, Giuliano Lantone, Vincenzo Lizzi, Miriam Cappiello, Marco Montagna, Fabio Pio Curci, Enrico Restini   +10 more
doaj   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source