Results 71 to 80 of about 802,447 (332)

Targeting the CMKLR1‐Mediated Signaling Rebalances Immunometabolism State in Middle‐Age Testicular Macrophages

open access: yesAdvanced Science, EarlyView.
In middle age, testicular CMKLR1⁺ macrophages exhibited a pro‐inflammatory immunometabolic profile, mediated by adipose signals associated with high BMI. However, inhibition of CMKLR1 signaling, either through Cmklr1 genetic ablation or treatment with a CMKLR1 antagonist peptide, can reverse this phenotype.
Zhendong Zhu   +10 more
wiley   +1 more source

First record of predation of Nyctinomops laticaudatus (É. Geoffroy, 1805) by Chrotopterus auritus (Peters, 1856) (Mammalia: Chiroptera) [PDF]

open access: yesBiodiversity Data Journal, 2019
The Wooly False Vampire Bat, Chrotopterus auritus (Peters, 1856) (Chiroptera: Phyllostomidae), feeds on small mammals, birds, lizards, frogs and occasionally large insects and fruits.
Ianna Borloti   +2 more
doaj   +3 more sources

A Novel CYP2E1 Inhibitor, 4‐Methyl‐5‐Acetylthiazole (Q11), Alleviates Obesity Via Modulating Adipose Inflammation and Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
Obesity involves chronic inflammation and mitochondrial dysfunction. This study identifies cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target in adipose tissue. Its activity increases in obese mice and correlates with inflammation and mitochondrial impairment.
Jinhuan Qiu   +10 more
wiley   +1 more source

Assessing the relationship between Body Mass Index and Bone Mineral Density in a clinical-based sample of Vietnamese aged 20–50: A generalized linear regression analysis

open access: yesHuman Nutrition & Metabolism
Background: While some evidence has shown that the BMI component differentially influences bone mineral density (BMD), no studies have examined the association between BMI and BMD in Vietnamese adults.
Trong Hung Nguyen   +6 more
doaj   +1 more source

Swift reveals the eclipsing nature of the high mass X-ray binary IGR~J16195-4945 [PDF]

open access: yes, 2016
IGR J16195-4945 is a hard X-ray source discovered by INTEGRAL during the Core Program observations performed in 2003. We analyzed the X-ray emission of this source exploiting the Swift-BAT survey data from December 2004 to March 2015, and all the ...
Cusumano, G.   +3 more
core   +2 more sources

Cidea Targeting Protects Cochlear Hair Cells and Hearing Function From Drug‐ and Noise‐Induced Damage

open access: yesAdvanced Science, EarlyView.
Acquired sensorineural hearing loss is primarily caused by the damage or loss of cochlear hair cells, induced by factors such as noise exposure and ototoxic drugs. The deficiency of apoptosis‐inducing gene Cidea in Cidea KO mice or by delivering CRISPR/SlugCas9‐HF via AAV to edit Cidea effectively alleviated hair cell damage and hearing loss caused by ...
Shasha Zhang   +14 more
wiley   +1 more source

Bat Boy Playbill [PDF]

open access: yes, 2018
Providence College Department of Theatre, Dance & Film Angell Blackfriars Theatre Smith Center for the Arts Bat Boy THE MUSICAL Directed by Jimmy Calitri Musical Direction by Lila Kane Music and lyrics by Laurence O’Keefe Story and book by Keythe Farley ...
Providence College
core   +1 more source

RHESSI Spectral Fits of Swift GRBs

open access: yes, 2008
One of the challenges of the Swift era has been accurately determining Epeak for the prompt GRB emission. RHESSI, which is sensitive from 30 keV to 17 MeV, can extend spectral coverage above the Swift-BAT bandpass. Using the public Swift data, we present
Claudia Wigger   +9 more
core   +1 more source

Bat flies (Diptera: Nycteribiidae and Streblidae) infesting cave-dwelling bats in Gabon: Diversity, dynamics and potential role in Polychromophilus melanipherus transmission [PDF]

open access: yes, 2016
Background Evidence of haemosporidian infections in bats and bat flies has motivated a growing interest in characterizing their transmission cycles.
Ayala, Diego   +9 more
core   +5 more sources

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