Results 141 to 150 of about 80,588 (268)

Trends and Challenges in Multistep Continuous Flow Synthesis. [PDF]

JACS Au
Chen J, Zou Y, Liao L, Yang B, Xing D, Zhou J, Qian X, Liu Y, He H, Gao S.   +9 more
europepmc   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Using <i>Novosphingobium aromaticivorans</i> for Concurrent Production of Intracellular and Extracellular Products from Aromatics Extracted from Poplar Biomass. [PDF]

ACS ES T Eng
Kim B, Hall BW, Haak DV, Coplien J, Karlen SD, Donohue TJ, Noguera DR.   +6 more
europepmc   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

Advanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi, Julia Di Stefano, Dearbhaile Dooley   +2 more
wiley   +1 more source

Expanding the Toolbox for Inducible Protein Expression With Automation-enabled Generation of Glycomimetics. [PDF]

Chemistry
DeYong AE, Marion KC, Ozturk M, Murali SK, Enam F, Mansell TJ, Pohl NLB.   +6 more
europepmc   +1 more source

A Synovium‐on‐Chip Platform to Study Multicellular Interactions in Arthritis

Advanced Healthcare Materials, EarlyView.
The Synovium‐on‐Chip comprises a thin microporous PDMS membrane to support co‐culture of fibroblast‐like synoviocytes (FLS), THP‐1‐derived macrophages, and endothelial cells, enabling real‐time analysis of synovial‐vascular interactions. FLS migration through the pores drives endothelial remodeling, while TNF‐α stimulation induces robust inflammatory ...
Laurens R. Spoelstra, Fleur R. Semmekrot, Nuno Araújo‐Gomes, Daniël Wijnperle, Monique M. A. Helsen, Martijn H.J. Van Den Bosch, Loes. I. Segerink, Séverine Le Gac, Marcel Karperien   +8 more
wiley   +1 more source

Selective Gas-Phase Ethylene Dimerization to 1-Butene in a Scalable Metal-Organic Framework. [PDF]

J Am Chem Soc
You E, Zhang X, Sarver P, Dincă M.
europepmc   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Advancing Raman Calibration: Automated Data Generation, Monitoring, and Control in Multi-Parallel Perfusion Mini Bioreactors. [PDF]

Biotechnol J
Machleid R, Goertz M, Grimm C, Trygg J, Mathias S, Surowiec I.   +5 more
europepmc   +1 more source

Accelerating the Transition Batch to Continuous in Pharmaceutically Relevant Hydrogenation Processes

Die Entwicklung von kontinuierlichen Prozessen in den feinchemischen und pharmazeutischen Industrien ist kritisch um schnellere, selektivere, sicherere und automatisierte Prozesse zu gewährleisten. Diese Doktorarbeit behandelt die Anwendung verschiedener Konzepte, wie z.b.
openaire