Results 41 to 50 of about 80,588 (268)

A Pitfall in Heavy Metal Separation with Amino‐modified Silica Adsorbents from Aqueous Solution: The Occurring pH Shift

open access: yesChemistryOpen, 2022
Selective separation of heavy metal ions from acidic aqueous solutions is of strong interest for certain industrial processes, such as electroplating, as well as environmental protection, for example battery recycling. Amino‐functionalized adsorbents are
Friederike Kriese   +2 more
doaj   +1 more source

Combination of Genome-Scale Models and Bioreactor Dynamics to Optimize the Production of Commodity Chemicals

open access: yesFrontiers in Molecular Biosciences, 2022
The current production of a number of commodity chemicals relies on the exploitation of fossil fuels and hence has an irreversible impact on the environment.
Jorge Lázaro   +6 more
doaj   +1 more source

Comparisons between continuous and batch processing to produce clavulanic acid by Streptomyces clavuligerus [PDF]

open access: yesBrazilian Archives of Biology and Technology, 2005
The aim of the present work was to compare CA production in continuous culture with and without cell recycling and in batch process by Streptomyces clavuligerus. Continuous cultivations with high cell concentration using cell recycling were performed utilizing a hollow fiber ultrafiltration module to separate cells from the filtrate broth.
Baptista-Neto, Álvaro   +4 more
openaire   +4 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte   +13 more
wiley   +1 more source

The History of Flow Chemistry at Eli Lilly and Company

open access: yesCHIMIA, 2023
Flow chemistry was initially used for speed to early phase material delivery in the development laboratories, scaling up chemical transformations that we would not or could not scale up batch for safety reasons.
Martin D. Johnson   +13 more
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

A versatile ceramic capillary membrane reactor system for continuous enzyme‐catalyzed hydrolysis

open access: yesEngineering in Life Sciences, 2021
As an alternative to classical batch processes, enzyme‐catalyzed hydrolysis can also be carried out continuously. To facilitate this, a continuous ceramic capillary membrane reactor system (CCCMRS) was developed which can be operated with various ...
Lorn Messner   +4 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Comparative Effect of UV, UV/H2O2 and UV/H2O2/Fe on Terbuthylazine Degradation in Natural and Ultrapure Water

open access: yesMolecules, 2022
Different advanced oxidation processes (AOPs) (ultraviolet radiation, hydrogen peroxide photolysis and photo-Fenton) were applied to test the degradation of terbuthylazine in three types of water: (a) ultrapure water, (b) surface water from the Gaditana ...
José Antonio Andrades   +3 more
doaj   +1 more source

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