Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez +6 more
wiley +1 more source
The value of EQ-5D-3L and EQ VAS as a patient-reported outcome measure for patients with ankylosing spondylitis in routine healthcare: an evaluation of construct validity and responsiveness based on the Swedish Rheumatology Quality Register. [PDF]
Degerlund-Maldi K +5 more
europepmc +1 more source
Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec +5 more
wiley +1 more source
Sulfolipid-1 from <i>Mycobacterium tuberculosis</i> activates Gαq/11-coupled pathways to increase sensory neuron excitability. [PDF]
Naik DK +10 more
europepmc +1 more source
Photothermal‐Activated Antibacterial Amyloid‐Polyphenol‐Iron Hydrogels for Synergistic Wound Healing
We report a thermally triggered supramolecular hydrogel (LTFe) formed by Fe3+ and tannic acid on lysozyme amyloid fibrils. Fe3+ enables rapid gelation and photothermal transduction with an efficiency of 88.56%. The LTFe hydrogel exhibits excellent biocompatibility, potent antibacterial activity against E. coli and S.
Di Wu +8 more
wiley +1 more source
Trajectory-based computational analysis of the quantum-classical transition in asymmetrically coupled spin-boson models. [PDF]
Uthailiang T, Issarakul P, Boonchui S.
europepmc +1 more source
Quick Rinse, Strong Bond? Comparing Short Water Rinsing and Advanced Cleaning Methods After Hydrofluoric Etching of Lithium Disilicate Glass Ceramic. [PDF]
Brandl V, Kern M, Schlenz MA, Wille S.
europepmc +1 more source
Clinical efficacy of tofacitinib in active ankylosing spondylitis and dynamic changes in gut microbiota: an exploratory descriptive four-case series with 16S rRNA sequencing analysis. [PDF]
Wang L, Xie W, Li J, Chen J, Huang Y.
europepmc +1 more source
Layered Gradient Grain Structure Enhances Mechanical Properties of Ultra-Thin Copper Foil. [PDF]
Wang X +11 more
europepmc +1 more source
Synthesis and Characterization of Nanostructured Thorium Carbide for Radioactive Ion Beam Production. [PDF]
Reis E +8 more
europepmc +1 more source

