Results 61 to 70 of about 275,494 (286)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Comparative Characteristics of the Bathing-beach Tourism in the Mediterranean and Pacific Regions [PDF]

, 2015
Здійснено характеристику Середземноморського та Тихоокеанського басейнів. Розкрито суть поняття купально-пляжний туризм, виділено три найважливіші світові регіони, що спеціалізуються на купально-пляжному туризмі.
Grechuha, O. V., Lepekha, M. S., Гречуха, О. В., Лепеха, М. С.   +3 more
core  

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

New system for bathing bedridden patients [PDF]

, 1973
Multihead shower facility can be used with minimal patient handling. Waterproof curtain allows patient to bathe with his head out of shower. He can move completely inside shower to wash his face and hair.
Greenleaf, J. E., Payne, P. A., Staley, R. A.   +2 more
core   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Effect of chlorhexidine wipe bath and bathing on prevention of central venous catheterrelated bloodstream infection in critically ill patients:a metaanalysis

Huli yanjiu, 2018
Objective:To evaluate the effect of chlorhexidine wipe bath and bathing in the prevention of central venous catheterrelated bloodstream infection(CLABSI)in critically ill patients.Methods:Literatures of potentially eligible citations investigated the ...
王娟, 马子英, 张爱华, 段燕
doaj  

Comparing the Effects of Swaddled and Conventional Bathing Methods on Body Temperature and Crying Duration in Premature Infants: A Randomized Clinical Trial [PDF]

Journal of Caring Sciences, 2014
Introduction: Maintaining body temperature and reducing stress are important challenges in bathing preterm infants. Swaddle bathing, which includes in itself the principles of developmental care, can be used as a low-stress and appropriate bathing method
Mitra Edraki, Maryam Paran, Sedigheh Montaseri, Mostajab Razavi Nejad, Zohre Montaseri   +4 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Springs as a Civilizing Mechanism in Daphnis and Chloe [PDF]

, 2017
: In Longus’ Daphnis and Chloe, springs are a central motif of the Prologue and the novel as a whole. This motif counters male domination, since it is associated with Chloe, while the flowers watered by springs in this novel are identified with Daphnis ...
Janelle Peters
core   +1 more source

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall, Cinthia Blat, Eric Roberts, Jean W. Liew, Katherine Wysham, Namrata Singh, Janna Friedly, Lianne S. Gensler, Gabriela Schmajuk, Jinoos Yazdany   +9 more
wiley   +1 more source