Results 31 to 40 of about 54,004 (259)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Historika : Studi di Storia Greca e Romana, 2013 CIL, V 5136 da Bergomum costituisce un'interessante testimonianza dell'evergetismo architettonico-termale in area transpadana. L'iscrizione evidenzia la concezione di un evergetismo privato improntato a criteri di pubblica utilità e prova il valore dell'
Paola Tomasi
doaj +1 more source
Avian Assemblages at Bird Baths: A Comparison of Urban and Rural Bird Baths in Australia. [PDF]
PLoS ONE, 2016 Private gardens provide habitat and resources for many birds living in human-dominated landscapes. While wild bird feeding is recognised as one of the most popular forms of human-wildlife interaction, almost nothing is known about the use of bird baths ...
Gráinne P Cleary +6 more
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Clinical researches on the efficacy of spa therapy in fibromyalgia: a systematic review
Annali dell'Istituto Superiore di Sanità, 2013 BACKGROUND: Fibromyalgia is characterized by chronic widespread pain, tenderness at muscle and tendon insertions point when digital pressure is applied, sleep disorders, chronic fatigue, depressive episodes, anxiety, and other functional somatic ...
Antonio Fraioli +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Warm sitz bath as an adjunctive therapy for distal ureteral calculi ≤5 mm: a prospective study
Frontiers in MedicineObjectiveTo evaluate the efficacy of warm sitz bath (WSB) as an adjunctive conservative therapy for patients with distal ureteral calculi (DUC) ≤5 mm.MethodsA total of 131 eligible patients with DUC ≤5 mm were prospectively randomized into the WSB group ...
Li-diao Li +5 more
doaj +1 more source