Results 61 to 70 of about 257,472 (267)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Incomplete current fluctuation theorems for a four-terminal model

, 2011
We demonstrate the validity of the current fluctuation theorem for a double quantum dot surrounded by four terminals within the Born-, Markov- and secular approximations beyond the Coulomb-blockade regime.
Brandes, Tobias, Krause, Thilo, Schaller, Gernot   +2 more
core   +1 more source

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall, Cinthia Blat, Eric Roberts, Jean W. Liew, Katherine Wysham, Namrata Singh, Janna Friedly, Lianne S. Gensler, Gabriela Schmajuk, Jinoos Yazdany   +9 more
wiley   +1 more source

A Birds Mosaic in Qalaat Seman

Journal of Mosaic Research, 2012
Pilgrims’ Baths are excavated since 2008 in Qalaat Seman, dating from the same period than the whole site (end of 5th century), they are partially dug. A large mosaic covers a courtyard surrounded by three galleries (circa 200 m2).
Marie-Patricia Raynaud
doaj  

Novel deep learning framework for detection of epileptic seizures using EEG signals

Frontiers in Computational Neuroscience
IntroductionEpilepsy is a chronic neurological disorder characterized by abnormal electrical activity in the brain, often leading to recurrent seizures.
Sayani Mallick, Veeky Baths
doaj   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

Effect on autonomic nervous activity of applying hot towels for 10 s to the back during bed baths

Journal of Physiological Anthropology, 2020
Background Bed baths are a daily nursing activity to maintain patients’ hygiene. Those may provide not only comfort but also relaxation. Notably, applying a hot towel to the skin for 10 s (AHT10s) during bed baths helped to reduce the risk of skin tears ...
Inaho Shishido, Issei Konya, Rika Yano
doaj   +1 more source

Duplex Stainless Steel Laser‐Surface Textured: Stability in Brine Solution

Advanced Engineering Materials, EarlyView.
Controlled laser‐surface treatment (LST) of duplex DSS2205 steel is performed to increase its stability in brine solution under cyclic electrochemical assays. The superior protection with respect to flat and smooth panels is attributed to the presence of FeCr2O4 as the main protective oxide layer in the LST surface, after corrosion tests. The stability
Mohammad Rezayat, Hamidreza Enshaei, Elaine Armelin, José I. Iribarren, Antonio Mateo, Miguel Morales   +5 more
wiley   +1 more source

Brownian Simulations and Uni-Directional Flux in Diffusion

, 2005
Brownian dynamics simulations require the connection of a small discrete simulation volume to large baths that are maintained at fixed concentrations and voltages.
A. Dvoretzky, A. Einstein, A. Singer, B. Hille, C. W. Gardiner, F. Langouche, H. Kleinert, K. Itô, L. S. Schulman, M. Freidlin, M. Kac, M. R. von Smolan Smoluchowski, M. R. von Smolan Smoluchowski, N. Wax, S. Karlin, S. Wigger-Aboud, Z. Schuss, Z. Schuss   +17 more
core   +1 more source