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Science's STKE, 2007
At about age 50, depletion of ovarian follicles through apoptosis leads to the loss of cyclic ovarian function in women. Menopause, in turn, is believed to set the stage for various health problems. Although aging female mice do not undergo menopause, they experience depletion of ovarian follicles and health complications similar to those ...
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At about age 50, depletion of ovarian follicles through apoptosis leads to the loss of cyclic ovarian function in women. Menopause, in turn, is believed to set the stage for various health problems. Although aging female mice do not undergo menopause, they experience depletion of ovarian follicles and health complications similar to those ...
openaire +2 more sources
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death
Cell, 1993Zoltán N. Oltval +2 more
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Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis
Science, 2004J. Chipuk +6 more
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Targeting BAX to drug death directly
Nature Chemical Biology, 2019L. Walensky
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BAX and BAK Regulation of Endoplasmic Reticulum Ca2+: A Control Point for Apoptosis
Science, 2003L. Scorrano +6 more
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Bax-Deficient Mice with Lymphoid Hyperplasia and Male Germ Cell Death
Science, 1995C. Knudson +4 more
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Apoptosis Initiated When BH3 Ligands Engage Multiple Bcl-2 Homologs, Not Bax or Bak
Science, 2007S. Willis +15 more
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