Results 111 to 120 of about 2,089,555 (322)

PM10 Impairs CD56dim NK Cell Cytotoxicity via FNBP1 Suppression to Exacerbate Rheumatoid Arthritis: Insights from Multimodal Multi‐Omics

Advanced Science, EarlyView.
This study, through multi‐omics approaches and animal models, revealed that air pollutant PM10 exacerbates the progression of rheumatoid arthritis (RA) by suppressing FNBP1 expression and impairing the cytotoxic function of CD56dim NK cells. The “PM10–FNBP1–NK cells” axis provided novel insights into the environmental pathogenesis of RA and suggested ...
Runhan Zhao, Qinyang Zhang, Yu Jiang, Dagang Tang, Xiao Qu, Jun Zhang, Yi Chen, Weixia Duan, Tao Li, Zhengwei Cai, Yanran Huang, Xiaoji Luo   +11 more
wiley   +1 more source

Editorial: Plastic Pollution in the Bay Areas

Frontiers in Marine Science, 2022
Xiaoshan Zhu, Xiaoshan Zhu, Xiangrong Xu, Lincoln Fok, Bin Cao, Daoji Li   +5 more
doaj   +1 more source

TÜRK MÜZİĞİNDE KÜRDÎ MAKAMININ TARİHSEL DEĞİŞİM VE DÖNÜŞÜMÜ ÜZERİNE BİR İNCELEME

Ayalgu Disiplinlerarası Türk Mûsikîsi Araştırmaları Dergisi, 2023
Zengin bir kültürel mirasa sahip olan Türk müziği, tarihsel süreçlerin etkisiyle şekillenmiş bir müzik geleneğidir. Bu geleneğin önemli bir unsuru olan makamlar da tarihsel süreç içerisinde değişim ve dönüşüme uğramışlardır.
Tolgahan Bay
doaj  

Biological characteristics of the catch from 1984-85 Pacific herring, Clupea harengus pallasi, roe fishery in California [PDF]

, 1984
In Tomales Bay, 5-, 6-, and 7-yr-old herring, Clupea harengus pallasi, composed 75% by number of the 1984-85 season's catch. In San Francisco Bay, 2-, 3-, and 4-yr-old herring composed 82% by number of the roundhaul catch, and 5-, 6-, and 7-yr-old ...
Spratt, Jerome D.
core   +1 more source

Long-Term Testing and Properties of Acrylic for the Daya Bay Antineutrino Detectors

, 2012
The Daya Bay reactor antineutrino experiment has recently measured the neutrino mixing parameter sin22{\theta}13 by observing electron antineutrino disappearance over kilometer-scale baselines using six antineutrino detectors at near and far distances ...
Heeger, K. M., Krohn, M., Littlejohn, B. R.   +2 more
core   +1 more source

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

Cuproptosis and Disulfidptosis Converge to Empower PD‐L1 Checkpoint Therapy via Cadict‐Induced PD‐L1 Translation

Advanced Science, EarlyView.
This study introduces Cadict, an EGFR‐targeted nanodrug that co‐delivers cuproptosis and disulfidptosis inducers to overcome immune resistance. Cadict synergistically enhances tumor cytotoxicity and sensitizes cancers to ICIs by upregulating PD‐L1 via an Eif5b‐dependent translation mechanism, fostering a potent antitumor immune response and ...
Shaoqing Huang, Shiyao Song, Xinhua Zhang, Jialing Gao, Ruihan Pu, Jiatong Dai, Xiaoxue Wu, Lulu Chen, Qinghai Li, Xiaoting Liu, Qi Zhou, Mei Song, Weiling He   +12 more
wiley   +1 more source

Part I. Hydraulics of tidal inlets: simple analytic models for the engineer [PDF]

, 1975
Inlets are common coastal features around the world. Essentially an inlet connects a lagoon, a bay or an estuary to the ocean (or sea), and the flow through the inlet channel is primarily induced by the tidal rise and fall of water level in the ocean.
Mehta, Ashish J.
core  

BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis

Cancer Research, 2004
S. Wilhelm, Christopher A. Carter, L. Tang, D. Wilkie, Angela Mcnabola, H. Rong, Charles Chen, Xiaomei Zhang, P. Vincent, M. McHugh, Yichen Cao, Jaleel Shujath, S. Gawlak, Deepa Eveleigh, B. Rowley, Li Liu, Lila Adnane, M. Lynch, D. Auclair, I. Taylor, R. Gedrich, A. Voznesensky, B. Riedl, L. Post, G. Bollag, P. Trail   +25 more
semanticscholar   +1 more source

Inhibition of Calcium‐Dependent Lipid Droplets Relocation of ACSL4‐PKCβ‐ALOX15 Complex Alleviates Ferroptosis and Acute Pancreatitis

Advanced Science, EarlyView.
This study identifies L‐type calcium channel blockers as novel ferroptosis inhibitors. It reveals that PKCβ, activated in calcium dependent manner, phosphorylates and activates ACSL4 and ALOX15, relocating them to lipid droplets to promote lethal lipid peroxidation and ferroptosis.
Guoyuan Hou, Jing Luan, Xiaoyong Xu, Jianhua Qin, Shuang Ma, Jiyuan He, Na Sun, Wei Zhang, Minghui Gao   +8 more
wiley   +1 more source