Results 81 to 90 of about 1,581,551 (302)

Exploring the Genetic Basis of Ketosis: Preliminary GWAS Findings on Beta-Hydroxybutyrate Levels in Holstein Cattle

open access: yesInternational Journal of Genomics
Ketosis is a metabolic condition characterized by a shift in energy metabolism, occurring when glucose availability is depleted and fat becomes the alternative primary energy source, resulting in the accumulation of ketone bodies.
Veysel Bay
doaj   +1 more source

A perspective on using experiment and theory to identify design principles in dye-sensitized solar cells

open access: yesScience and Technology of Advanced Materials, 2018
Dye-sensitized solar cells (DSCs) have been the subject of wide-ranging studies for many years because of their potential for large-scale manufacturing using roll-to-roll processing allied to their use of earth abundant raw materials. Two main challenges
Peter J. Holliman   +9 more
doaj   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

open access: yesAdvanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su   +10 more
wiley   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao   +11 more
wiley   +1 more source

Crommet Creek Conservation Area Management Plan [PDF]

open access: yes, 2012
The Crommet Creek Conservation Area comprises the largest block of natural lands in the immediate Great Bay watershed, and in New Hampshire’s North Atlantic Coast Ecoregion. It includes the entire watershed of two tidal creeks that flow directly into the
Brickner-Wood, Dea   +5 more
core   +2 more sources

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

open access: yesAdvanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija   +22 more
wiley   +1 more source

Biological characteristics of the catch from the 1990-91 Pacific Herring, Clupea pallasi, roe fishery in California [PDF]

open access: yes, 1991
The Tomales-Bodega Bay catch during the past two seasons has been from the northern part of Bodega Bay, due to the closure of the Tomales Bay fishery.
Spratt, Jerome D.
core  

The hunt for theta13 at the Daya Bay nuclear power plant

open access: yes, 2009
The Daya Bay reactor neutrino experiment is located at the Daya Bay nuclear power plant in Shenzhen, China. The experiment deploys eight "identical" antineutrino detectors to measure antineutrino fluxes from six 2.9 GW_{th} reactor cores in three ...
Wang, Wei
core   +1 more source

Cuproptosis and Disulfidptosis Converge to Empower PD‐L1 Checkpoint Therapy via Cadict‐Induced PD‐L1 Translation

open access: yesAdvanced Science, EarlyView.
This study introduces Cadict, an EGFR‐targeted nanodrug that co‐delivers cuproptosis and disulfidptosis inducers to overcome immune resistance. Cadict synergistically enhances tumor cytotoxicity and sensitizes cancers to ICIs by upregulating PD‐L1 via an Eif5b‐dependent translation mechanism, fostering a potent antitumor immune response and ...
Shaoqing Huang   +12 more
wiley   +1 more source

Factors affecting estuarine populations of Nereocystis luetkeana in Kachemak Bay, Alaska [PDF]

open access: yes, 2003
Thesis (M.S.) University of Alaska Fairbanks, 2003Nereocystis luetkeana forms extensive kelp beds in Kachemak Bay, Alaska. Salinity and turbidity gradients apparently regulate kelp bed distribution throughout this estuary.
Chenelot, Héloïse Anne Claude
core  

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