Results 51 to 60 of about 1,723,352 (285)

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

A Bayes Linear Bayes Method for Estimation of Correlated Event Rates [PDF]

Risk Analysis, 2013
Typically, full Bayesian estimation of correlated event rates can be computationally challenging since estimators are intractable. When estimation of event rates represents one activity within a larger modeling process, there is an incentive to develop more efficient inference than provided by a full Bayesian model.
Quigley, John, Wilson, Kevin, Walls, Lesley, Bedford, Tim   +3 more
openaire   +4 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Merging expert and empirical data for rare event frequency estimation : pool homogenisation for empirical Bayes models [PDF]

, 2011
Empirical Bayes provides one approach to estimating the frequency of rare events as a weighted average of the frequencies of an event and a pool of events. The pool will draw upon, for example, events with similar precursors.
Hardman, Gavin, Bedford, Tim, Quigley, John, Walls, Lesley   +3 more
core   +4 more sources

Tempering the Bayes Filter Towards Improved Model-Based Estimation

IEEE Open Journal of Control Systems
Model-based filtering is often carried out while subject to an imperfect model, as learning partially-observable stochastic systems remains a challenge.
Menno J. T. C. van Zutphen, Domagoj Herceg, Giannis Delimpaltadakis, Duarte J. Antunes   +3 more
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Bayesian Estimation for Inverse Weibull Distribution Under Progressive Type-II Censored Data With Beta-Binomial Removals

Austrian Journal of Statistics, 2018
This paper deals with the estimation procedure for inverse Weibull distribution under progressive type-II censored samples when removals follow Beta-binomial probability law. To estimate the unknown parameters, the maximum likelihood and Bayes estimators
Pradeep Kumar Vishwakarma, Arun Kaushik, Aakriti Pandey, Umesh Singh, Sanjay Kumar Singh   +4 more
doaj   +1 more source

Statistical inference with joint progressive censoring for two populations using power Rayleigh lifetime distribution

Scientific Reports, 2023
In this study, point and interval estimations for the power Rayleigh distribution are derived using the joint progressive type-II censoring technique. The maximum likelihood and Bayes methods are used to estimate the two distributional parameters.
Ahlam H. Tolba, Tahani A. Abushal, Dina A. Ramadan   +2 more
doaj   +1 more source

Bayes Estimates for the Linear Model

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1972
Summary The usual linear statistical model is reanalyzed using Bayesian methods and the concept of exchangeability. The general method is illustrated by applications to two-factor experimental designs and multiple regression.
Lindley, D. V., Smith, A. F. M.
openaire   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source