Empirical Bayes estimation of farm prevalence adjusting for multistage sampling and uncertainty in test performance: a Brucella cross-sectional serostudy in southern Kazakhstan. [PDF]
Beauvais W, Orynbayev M, Guitian J.
europepmc +1 more source
Aims In the AEGEAN study, perioperative durvalumab plus platinum‐based neoadjuvant chemotherapy for patients with resectable stage II to IIIB (N2) non‐small‐cell lung cancer (NSCLC) demonstrated a favourable benefit–risk profile. This study evaluated population pharmacokinetics (PopPK) and exposure–response (ER) relationships of durvalumab in patients ...
Xiaoying Zhao +12 more
wiley +1 more source
Fast 3D-HEVC Depth Map Coding Method Based on Spatio-Temporal Correlation and a Two-Stage Mode Decision Framework. [PDF]
Tian E, Zhang J, Zhang Q.
europepmc +1 more source
A real‐world data‐driven approach to optimizing enoxaparin dosing in burn patients
Aim Enoxaparin dosing in burn patients is challenging due to physiological changes affecting absorption, distribution and clearance. The objectives of this study are to develop a population pharmacokinetic (PK) model for enoxaparin in burn patients, evaluate target attainment with current equation‐based (EQ) dosing and propose an optimized dosing ...
Babajide Shenkoya +3 more
wiley +1 more source
Effect of enzalutamide on anticoagulant therapy with edoxaban in patients with prostate cancer
Aims Treatment with enzalutamide in prostate cancer is challenging due to its high potential for drug–drug interactions, particularly in the typically older population of patients with frequent comorbidities treated with multiple drugs, such as anticoagulants.
Catharina J. P. Op 't Hoog +8 more
wiley +1 more source
Bayesian and non-Bayesian estimation of the bivariate inverse Weibull distribution parameters using ranked set sampling with concomitant variable. [PDF]
Muhammed HZ, Shaaban M.
europepmc +1 more source
Abstract Aims Andexanet alfa was recommended by the National Institute for Health and Clinical Excellence (NICE) as an option in the management of life‐threatening gastrointestinal bleeding in patients taking apixaban or rivaroxaban in May 2021. A recent UK‐wide survey of local hospital protocols for the use of andexanet alfa suggested that practice ...
Louis Fisher +11 more
wiley +1 more source
Bayes Factor Tests for Group Differences in Ordinal and Binary Graphical Models. [PDF]
Marsman M +3 more
europepmc +1 more source
Abstract Congenital ichthyoses (CI) are rare, inherited skin disorders characterized by hyperkeratosis, scaling and fissuring that significantly impair patients' quality of life. Treatment options are limited, with systemic retinoids reserved for severe cases owing to their adverse effect profile.
Holm Schneider +10 more
wiley +1 more source
Comparing Bayesian estimation and structural-after-measurement approaches for structural equation models with latent interactions and complex data structures. [PDF]
Cox K, Kelcey B.
europepmc +1 more source

