Results 171 to 180 of about 212,322 (298)

An Assessment of Reliability Estimation Methods for Binomial Health Care Quality Measures. [PDF]

Stat Med
Aume L, White W, Chen PH, Geppert J.
europepmc   +1 more source

Reducing Ion Transport Friction by Mitigated Diluent‐Solvent Interaction for Sodium–Sulfur Battery

Advanced Science, EarlyView.
A local high‐concentration electrolyte to balance the ionic conductivity and interfacial stability is developed through replacing the high solvating DME with the moderate solvating diethyl ether to mitigate the diluent‐solvent interaction and reduce the local dynamic friction for Na+ transport, while maintaining the anion‐rich solvation clusters and ...
Sihang Xia, Jia Xu, Songling Wu, Shanshan Cao, Zhanju Wang, Xiangyang Gu, Jiang Liang, Kangning Zhao, Weina Xu, Chao Yang   +9 more
wiley   +1 more source

Bayesian perspective for orientation determination in cryo-EM with application to structural heterogeneity analysis. [PDF]

Acta Crystallogr D Struct Biol
Xu S, Balanov A, Singer A, Bendory T.
europepmc   +1 more source

Oligosaccharides With Defined Glycosidic Bonds Shape Gut Microbial Succession and Metabolism Via Bond‐Specific Microbial Responders

Advanced Science, EarlyView.
Oligosaccharides with defined glycosidic bonds drive divergent gut microbial succession and shape unique metabolic profiles. Absolute time‐series profiling with Bayesian generalized Lotka–Volterra modeling identifies bond‐specific microbial responders, while monoculture validation and metaproteomics reveal linkage‐matched transport and cleavage modules.
Xiaoxuan Lu, Jiaqi Zou, Geng Han, Mengyao Zhao, Ting Luo, Xiangru Feng, Liangliang Zhu, Yijia Chen, Xiaoguo Ji, Jiayang Jin, Liming Zhao   +10 more
wiley   +1 more source

Simulation-based approach with an adaptive Type-II hybrid progressive censoring scheme to study the coefficient of variation of the weighted exponential distribution. [PDF]

PLoS One
Aljohani HM, Alharthi AS, Almohri WAJ, Aljeddani SMA, Alsubaie NE, El-Sharkawy WA.   +5 more
europepmc   +1 more source

On improving standard estimators via linear empirical Bayes methods

Suppose one wishes to estimate the parameter [theta] in a current experiment when one also has in hand data from k past experiments satisfying empirical Bayes sampling assumptions.
Samaniego, Francisco J., Vestrup, Eric
core  

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Classical and Bayesian reliability inference for the chen distribution under a block-adaptive progressive hybrid censoring plan. [PDF]

PLoS One
El-Awady MM, Ahmad HH, Ramadan DA, Elnagar KA.   +3 more
europepmc   +1 more source

YTHDC1 Orchestrates Glucose and Glutamate Rewiring to Overcome Lethal Metabolic Stress in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Lai et al. find that m6A reader YTHDC1 is specifically overexpressed in triple‐negative breast cancer (TNBC) and orchestrates glucose and glutamine metabolism in an m6A‐dependent manner to confer robust adaptability to lethal metabolic stress. Leveraging YTHDC1 knockdown‐induced metabolic vulnerability, an ATF4 mRNA‐targeted nanotherapy is developed to
Zheng‐Hao Lai, Yi Wang, Na‐Na Li, Ling Zeng, Renzhong Liu, Xue Li, Cheukfai Li, Xin‐Yu Ma, Wenkui Fu, Yingsen Tang, Jinjin Chen, Ning Liao, Man‐Li Luo   +12 more
wiley   +1 more source

Empirical Bayes minimax estimators of matrix normal means

The paper considers estimation of matrix normal means. A class of empirical Bayes estimators is proposed which dominates the maximum likelihood estimator simultaneously for many quadratic losses.
Shieh, Gwowen, Ghosh, Malay
core