Results 31 to 40 of about 307,150 (219)

Conceptual Challenges on the Road to the Multiverse

Universe, 2019
The current debate about a possible change of paradigm from a single universe to a multiverse scenario could have deep implications on our view of cosmology and of science in general. These implications therefore deserve to be analyzed from a fundamental
Ana Alonso-Serrano, Gil Jannes
doaj   +1 more source

Introducing augmented reality in early childhood literacy learning

Research in Learning Technology, 2021
Augmented reality (AR) as an emerging technology has gradually been incorporated into educational contexts; however, the cases that incorporate AR into early childhood contexts are underrepresented and especially scant in the literacy domain.
Zilong Pan, Mary Frances López, Chenglu Li, Min Liu   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Analyzing rotational bands in odd-mass nuclei using effective field theory and Bayesian methods

Frontiers in Physics, 2022
We recently developed an Effective Field Theory (EFT) for rotational bands in odd-mass nuclei. Here we use EFT expressions to perform a Bayesian analysis of data on the rotational energy levels of 99Tc, 155,157Gd, 159Dy, 167,169Er, 167,169Tm, 183W, 235U ...
I. K. Alnamlah, I. K. Alnamlah, E. A. Coello Pérez, D. R. Phillips   +3 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Evolutionary Tree for All Bumblebee Species World-Wide Estimated by Combining Information from Fast-Evolving Genes, Slow-Evolving Genes, and Genomic Data (Apidae, Bombus)

Insects
Evolutionary trees are of central importance in biology to develop explanatory frameworks for many kinds of studies, including studies of behaviour, ecology, and conservation.
Paul H. Williams, Pedro Alonso-Alonso, Marina Arbetman, Elaine Françoso, Guillaume Ghisbain, Jiaxing Huang, Michael C. Orr, Zong-Xin Ren, Martin Streinzer, Chawatat Thanoosing, Rémy Vandame, Madeleine Waite, Selina Brace   +12 more
doaj   +1 more source

Identification of associated risk factors for the severity of generalized anxiety disorder among Iranian infertile people: An ordinal regression analysis with a flexible link function

Journal of Research in Medical Sciences, 2019
Background: Generalized anxiety disorder (GAD) is a common disorder in infertile people. The aim of this study was the identification of associated risk factors for the severity of GAD in infertile people using an ordinal model with a flexible link ...
Fatemeh Mohammadzadeh, Ebrahim Hajizadeh, Aliakbar Rasekhi, Reza Omani-Samani   +3 more
doaj   +1 more source

Bayesian Network Model to Evaluate the Effectiveness of Continuous Positive Airway Pressure Treatment of Sleep Apnea [PDF]

Healthcare Informatics Research, 2018
ObjectivesThe association between obstructive sleep apnea (OSA) and mortality or serious cardiovascular events over a long period of time is not clearly understood.
Olli-Pekka Ryynänen, Timo Leppänen, Pekka Kekolahti, Esa Mervaala, Juha Töyräs   +4 more
doaj   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source