Results 151 to 160 of about 68,993 (274)

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

open access: yesCell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang   +10 more
wiley   +1 more source

Analysis of the relationship between firm innovation and corporate social responsibility: A systematic literature review

open access: yesEuropean Management Review, EarlyView.
Abstract Firm innovation and corporate social responsibility (CSR) are key strategic considerations that shape a firm's competitiveness and sustainability. However, studies exploring the relationship between the two are heterogeneous and sometimes obtain contradictory results, making it difficult to draw clear conclusions.
Daniel Alonso‐Martínez   +2 more
wiley   +1 more source

Discovery of a cryptic aminoacidic triad involved in the temperature adaptation of GH1 enzymes

open access: yesThe FEBS Journal, EarlyView.
Cold‐active enzymes retain high catalytic activity at low temperatures but are characterized by thermal instability, a behavior not fully understood. Comparison between a cold‐active GH1 and its mesophilic counterparts highlights the role of a three‐residue motif (W‐M‐F) in conferring structural stability to a mesophilic GH1.
Stefania Digiovanni   +5 more
wiley   +1 more source

Dynamic Capabilities as Drivers of Circular Business Models: Exploring Direct and Indirect Relationships

open access: yesJournal of Product Innovation Management, EarlyView.
ABSTRACT Academic Summary Despite the urgent need for a circular economy, firms' transition from linear to circular business models (CBMs) remains slow. While previous research suggests that dynamic capabilities are the key drivers of this transition, it assumes a direct link, overlooking that these capabilities can facilitate change but do not ...
Jörn Block   +4 more
wiley   +1 more source

Novel Hydrurus species (Chrysophyceae) and their adaptations to high‐altitude European and Arctic snowfields

open access: yesJournal of Phycology, EarlyView.
Abstract Colored snow caused by green algae (Chlorophyceae) is well known, but melting snowpacks can also harbor golden‐brown blooms consisting of Chrysophyceae. We collected 14 samples of cryoflora in the Austrian and Swiss Alps, the High Tatras in Slovakia, and in Arctic Svalbard. Eight laboratory unicellular flagellated strains were established from
Lenka Procházková   +6 more
wiley   +1 more source

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