Results 121 to 130 of about 536,624 (300)

Nano‐Confined Radical Anion as An NIR‐II Photothermal Immunogenic Amplifier for In Situ Cancer Vaccination

open access: yesAdvanced Science, EarlyView.
A nano‐confined radical anion acts as a photothermal immunogenic amplifier. Kinetically stabilized nanoparticles couple high near‐infrared‐II (NIR‐II) photothermal efficacy with glutathione (GSH) depletion to boost reactive oxygen species (ROS) and immunogenic cell death (ICD).
Mengxin Mu   +9 more
wiley   +1 more source

Thermally Driven Supramolecular Chirality Evolution in Low‐Bandgap Fused‐Ring Conjugated Molecules for High‐Performance NIR Circularly Polarized Light Detection

open access: yesAdvanced Science, EarlyView.
A supramolecular chirality evolution strategy in chiral low‐bandgap fused‐ring conjugated molecules enables high‐performance near‐infrared (NIR) circularly polarized light photodetection. Halogen substitution and thermal annealing induce chiral amplification and hierarchical ordering. Integrated into Schottky barrier vertical transistors, the optimized
Jaeyong Ahn   +6 more
wiley   +1 more source

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

open access: yesAdvanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding   +7 more
wiley   +1 more source

Effect of New Structures at Headland of Crenulate-Shaped Bays on the Equilibrium Shape of Bays in Mokran Coasts

open access: yesInternational Journal of Coastal and Offshore Engineering, 2019
Construction of a new coastal structure changes the stable shape of the shoreline. This issue generally leads to sedimentation and erosion around adjacent structures due to changes in Littoral Sediment Transport (LST). This mechanism is considerably more
Mohammad Arian   +2 more
doaj  

Targeted Delivery of Indole‐3‐Pyruvic Acid Suppresses Macrophage Ferroptosis to Enhance CD8+ T Cell‐Mediated Immunotherapy Response in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
A microbiota‐derived metabolite, indole‐3‐pyruvic acid, suppresses macrophage ferroptosis through the AHR–NF‐κB–SLC7A11 axis. This preserves CD8+ T cell function in bladder cancer. Macrophage‐targeted nanoparticles enhance indole‐3‐pyruvic acid delivery and overcome resistance to PD‐1 blockade.
Jianwen Lao   +15 more
wiley   +1 more source

Bioinspired Passive Flow Routing to Mitigate Thrombosis in Prosthetic Heart Valves and Cardiovascular Devices

open access: yesAdvanced Science, EarlyView.
Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin   +8 more
wiley   +1 more source

Correction: Quality of life improvements associated with weight loss using a novel shape-shifting hydrogel capsule: RESET study results. [PDF]

open access: yesInt J Obes (Lond)
Kushner RF   +10 more
europepmc   +1 more source

Bidirectional Disulfide Metathesis Enables Recycling of High‐Performance Thermoset Networks

open access: yesAdvanced Science, EarlyView.
A cyclic aromatic disulfide comonomer enables dual‐mode recyclable pDCPD thermosets through bidirectional disulfide metathesis. The resulting networks combine enhanced mechanical performance with thermal reprocessability and chemical depolymerization into reusable oligomeric fragments, allowing regeneration of high‐performance thermosets with minimal ...
Bohan Li   +8 more
wiley   +1 more source

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