Results 11 to 20 of about 7,746 (196)

Structure-guided protein design of fluoroacetate dehalogenase for kinetic resolution of rac-2-bromobutyric acid

open access: yesGreen Synthesis and Catalysis, 2020
R-2-Bromobutyric acid is a very important intermediate for the synthesis of agrochemicals and pharmaceuticals. Bioresolution of rac-2-bromobutyric acid (rac-2-BBA) provides a promising process for R-2-bromobutyric acid (R-2-BBA) production.
Shu Wang   +6 more
doaj   +1 more source

Sedimentary Mercury Enrichments as a Tracer of Large Igneous Province Volcanism

open access: yesGeophysical Monograph Series, Page 247-262., 2021

Exploring the links between Large Igneous Provinces and dramatic environmental impact

An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Lawrence M. E. Percival   +3 more
wiley  

+1 more source

bba, a synthetic derivative of 23-hydroxybutulinic acid, reverses multidrug resistance by inhibiting the efflux activity of MRP7 (ABCC10).

open access: yesPLoS ONE, 2013
Natural products are frequently used for adjuvant chemotherapy in cancer treatment. 23-O-(1,4'-bipiperidine-1-carbonyl) betulinic acid (BBA) is a synthetic derivative of 23-hydroxybutulinic acid (23-HBA), which is a natural pentacyclic triterpene and the
Jun-Jiang Chen   +11 more
doaj   +1 more source

Direct cover-clip for ICA blood blister-like aneurysm

open access: yesInterdisciplinary Neurosurgery, 2019
Blood blister aneurysm (BBA) is the aneurysm characterized by fragile neck usually arising from the dorsal wall of internal carotid artery (ICA). Application of aneurysm clip on the neck of BBA usually tears out the wall of the parent artery, leaving a ...
Songping Zheng, M.D.   +2 more
doaj   +1 more source

Query Expansion for Effective Retrieval Results of Hindi–English Cross-Lingual IR

open access: yesApplied Artificial Intelligence, 2019
Information retrieval (IR) is the science of identifying documents or sub-documents from a collection of information or database. The collection of information does not necessarily be available in only one language as information does not depend on ...
Ganesh Chandra, Sanjay K. Dwivedi
doaj   +1 more source

Willis covered stent in the treatment of a recurrent blood blister-like aneurysm after pipeline implementation: A case report

open access: yesJournal of Interventional Medicine, 2023
Blood blister-like aneurysms (BBAs) are fragile and difficult to treat. However, the optimal treatment has yet to be determined. Pipeline embolization devices and Willis covered stent implementation are still controversial strategies for treating BBA ...
Yu Fu, Feng Fan, Jing Li, Sheng Guan
doaj   +1 more source

Turning Back the Clock: A Retrospective Single-Blind Study on Brain Age Change in Response to Nutraceuticals Supplementation vs. Lifestyle Modifications

open access: yesBrain Sciences, 2023
Background: There is a growing consensus that chronological age (CA) is not an accurate indicator of the aging process and that biological age (BA) instead is a better measure of an individual’s risk of age-related outcomes and a more accurate predictor ...
Andrew A. Fingelkurts   +1 more
doaj   +1 more source

Secondary Site Ligand for Integrin αVβ3 Enables Targeted mRNA Delivery

open access: yesAngewandte Chemie, EarlyView.
Non‐orthosteric, low‐affinity ligands for integrin αVβ3, identified by fragment screening, achieve superselective nanoparticle targeting (ακ ≈ 3) of αVβ3‐overexpressing endothelial cells. Unlike traditional arginine–glycine–aspartate decorated particles, these fragment‐functionalized LNPs discriminate cells by receptor density and deliver mRNA to ...
Sebastian Bayer   +7 more
wiley   +2 more sources

Beyond the Fixed Charge: A New On‐Tissue Derivatisation Strategy Employing Photoionisable Chromophores for Mass Spectrometry Imaging of Amino‐Containing Metabolites

open access: yesAngewandte Chemie, EarlyView.
We introduce a novel chemical derivatisation strategy for the UV‐activated detection of elusive metabolites. Incorporation of a tocopherol‐active chromophore allows for the detection of tagged analytes as photoionised radical cations, selectively induced by a 266 nm laser.
Sofia R. McGowan   +5 more
wiley   +2 more sources

Multi-level Fuzzy system for usable-security assessment

open access: yesJournal of King Saud University: Computer and Information Sciences, 2022
Indubitably, security is an integral aspect of the development of quality software. More importantly, usability is also an elemental and pivotal factor for developing quality software.
Alka Agrawal   +4 more
doaj   +1 more source

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