Results 131 to 140 of about 44,754 (289)

sGC stimulator BAY 41‐8543 improves survival and ventricular function in a rat model of doxorubicin‐induced cardiomyopathy with nephrotic syndrome

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Anthracyclines such as doxorubicin (DOXO) remain a cornerstone of cancer therapy but are associated with a high risk of cardiotoxicity and subsequent heart failure (HF). Impairment of NO/soluble guanylyl cyclase (sGC)/cGMP pathway has been reported in anthracycline‐induced cardiomyopathy.
Olga Gawrys   +14 more
wiley   +1 more source

Making BBS Anonymous Credentials eIDAS 2.0 Compliant [PDF]

open access: yes
eIDAS 2.0 (electronic IDentification, Authentication and trust Services) is a very ambitious regulation aimed at equipping European citizens with a personal digital identity wallet (EU Digital Identity Wallet) on a mobile phone that not only needs to ...
Jacques Traoré   +3 more
core  

Validation of the Birth Beliefs Scale for maternity care professionals in The Netherlands

open access: yesJournal of Psychosomatic Obstetrics and Gynecology
Objectives To validate the Birth Beliefs Scale (BBS) for maternity care professionals by testing: (1) content validity; (2) internal reliability; (3) known-group discriminant validity; and examine potential relationships between regions and birth beliefs.
Dirkje C. Zondag   +5 more
doaj   +1 more source

Strictly Conservative Neural Distance Fields

open access: yesComputer Graphics Forum, EarlyView.
Abstract We propose a first method to generate neural unsigned or signed distance fields (SDFs) that are guaranteed to be conservative with respect to a given 3D shape. This means the true distance is never overestimated and the zero‐level set is a bounding volume for the shape. The method makes use of neural network architectures that ensure Lipschitz
I. Ludwig, M. Campen
wiley   +1 more source

World Health Organization Healthy Ageing model applied to adults with cerebral palsy: A systematic review of reported intrinsic capacity measures

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This systematic review reports on quantitative measures of intrinsic capacity domains of the WHO Healthy Ageing model for adults with CP. Reports from 102 studies showed reduced locomotor, vitality andn possibly cognitive intrinsic capacity reserves for adults aged 30–45 years.
Woroud Alzaher   +4 more
wiley   +1 more source

BBS-harrastus Suomessa 1993-1999: havaintoja toiminnan piirteistä ja muutoksista [PDF]

open access: yes, 2007
BBS activity in Finland between 1993 and 1999 The BBS (Bulleting Board System) activity – that had emerged out of need for communication between microcomputer enthusiasts – landed in Finland at the beginning of the 1980s.
Hirvonen, Mikko
core   +1 more source

The compounding effects of accumulated perceived employer exploitation when tough business decisions must be made

open access: yesEuropean Management Review, EarlyView.
Abstract We examine how a single exploitative employer decision event, conceptualized as a shock, interacts with employees' accumulated perceived employer exploitation to amplify feelings of violation and influence adverse employee reactions. This interaction effect, and its boundary conditions, constitutes the primary theoretical contribution of the ...
Dorothea Roumpi   +3 more
wiley   +1 more source

Role proteinového komplexu BBS v T lymfocytech [PDF]

open access: yes, 2018
BBSome is a protein complex crucial for trafficking of specific cargoes to the primary cilium. Although primary cilia are typically not present in cells of haematopoietic origin, such as T cells, recent research has revealed striking parallels between ...
Niederlová, Veronika
core  

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

open access: yesThe FEBS Journal, EarlyView.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh   +7 more
wiley   +1 more source

Framework for headache management in pediatric patients with stroke and cerebrovascular lesions: A narrative review

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To present a practical, evidence‐based framework for the management of headache disorders in pediatric patients with prior stroke or underlying cerebral vascular lesions, with particular attention to safety and efficacy of pharmacologic and non‐pharmacologic therapies.
Allison C. Hyland   +7 more
wiley   +1 more source

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