Results 151 to 160 of about 219,243 (185)

Can Environmental Enrichment Mitigate Cell Apoptosis in the Central Nervous System Under Adverse Health Conditions? A Systematic Review. [PDF]

Clin Transl Sci
de Sousa Fernandes MS, Ferreira DJS, Yagin FH, Badicu G, Santos GCJ, Guedes MCS, Souto FO, Ardigò LP.   +7 more
europepmc   +1 more source

Molecular Effect of Tobacco on Genetic, Epigenetic, and Metabolic Pathways During Cancer Progression. [PDF]

Cureus
Kumar U, Jahnavi G, Biswas B, Alam B, Varshney S.   +4 more
europepmc   +1 more source

Resistance to Targeted Therapy in AML: Current Challenges and Emerging Treatment Strategies. [PDF]

J Clin Med
Stafylidis C, Diamantopoulos PT.
europepmc   +1 more source

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Oligomerization process of Bcl-2 associated X protein revealed from intermediate structures in solution

Physical Chemistry Chemical Physics, 2017
Linear oligomerization of ditopic BAX-dimers into tri-dimer helical units then into a rod-like structure, as revealed using integrated ESR/SAXS/MD analyses.
Orion Shih, Yi-Qi Yeh, Kuei-Fen Liao, Tai-Ching Sung, Yun-Wei Chiang, U-Ser Jeng   +5 more
openaire   +2 more sources

Long noncoding RNA DINO (damage induced noncoding) represses the development of gastric cancer by modulating p21 and Bcl‐2 Associated X Protein (Bax) expression

Journal of Cellular Biochemistry, 2019
AbstractlncRNAs are responsible for a variety of diseases, including gastric cancer (GC). Many recent studies have reported that lncRNAs can serve as crucial regulators of various genes. Nevertheless, the biological function of lncRNA damage induced noncoding (DINO) remained poorly investigated in GC.
Qinqiang Liu, Yan Xiao, Peng Cai, Jun Li, Dawei Li   +4 more
openaire   +2 more sources

BIM (BCL-2 interacting mediator of cell death) SAHB (stabilized α helix of BCL2) not always convinces BAX (BCL-2-associated X protein) for apoptosis

Journal of Molecular Graphics and Modelling, 2016
The interaction of BAX (BCL-2-associated X protein) with BIM (BCL-2 interacting mediator of cell death) SAHB (stabilized α helix of BCL2) directly initiates BAX-mediated mitochondrial apoptosis. This molecular dynamics study reveals that BIM SAHB forms a stable complex with BAX but it remains in a non-functional conformation.
Sharad, Verma, Sukriti, Goyal, Chetna, Tyagi, Salma, Jamal, Aditi, Singh, Abhinav, Grover   +5 more
openaire   +2 more sources