Results 61 to 70 of about 1,954 (193)
CYTOTOXIC ACTIVITY OF Anredera cordifolia LEAF EXTRACT ON HELA CELLS
Cervical cancer is the second most frequently occurring cancer among females all over the world. Since the best strategy against cancer is to kill the cancer cells without endangering the normal cells, discovering a potentially selective anticancer ...
Dita Maria Virginia +2 more
doaj +1 more source
Next‐Generation Bio‐Reducible Lipids Enable Enhanced Vaccine Efficacy in Malaria and Primate Models
Structure–activity relationship (SAR) optimization of bio‐reducible ionizable lipids enables the development of highly effective lipid nanoparticle (LNP) mRNA vaccines. Lead LNPs show superior tolerability and antibody responses in rodents and primates, outperforming approved COVID‐19 vaccine lipids.
Ruben De Coen +30 more
wiley +1 more source
Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain
Abstract Background In mammals, specific brain regions such as the dentate gyrus (DG) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricles harbor adult neural stem/progenitor cells (ANSPCs) that give rise to new neurons and contribute to structural and functional brain plasticity.
Diana Zhilina +12 more
wiley +1 more source
Anthrax infection is primarily initiated by B. anthracis endospores that on entry into the host germinate to vegetative cells and cause severe bacteremia and toxaemia employing an array of host colonisation factors and the lethal tripartite toxin.
Saugata Majumder +5 more
doaj +1 more source
Development of a 21-miRNA Signature Associated With the Prognosis of Patients With Bladder Cancer
Objective: To develop a prognostic signature for patients with bladder cancer (BC).Methods: We identified differentially expressed miRNAs between normal bladder tissue and bladder cancer in the TCGA-BCLA dataset and evaluated prognostic values of these ...
Xiao-Hong Yin +14 more
doaj +1 more source
Epidemiology and Economic Burden of Sleep Disorders in Europe
We investigated the epidemiology and costs of five major sleep disorders in Europe using systematic literature reviews, data harmonization, and imputation. Estimated adult prevalence was 18% for OSA, 10% for insomnia, 3% for RLS, 0.03% for narcolepsy, and 0.009% for RBD. In 2019, OSA had the highest economic impact in high‐income Europe (€184 billion),
Claudio L. A. Bassetti +14 more
wiley +1 more source
Driver state detection in port quayside cranes faces challenges from complex cockpit backgrounds and lightweight deployment needs. We proposed a lightweight detection network BVGA-Net based on an improved receptive-field attention mechanism and multi ...
Yong Zhang +9 more
doaj +1 more source
BCLA Volunteer Feature: Nancy Hannum
A new feature for the BCLA Browser, featuring stories from volunteers who have made a difference in BC's Library ...
Hannum, Nancy, Wass (Editor), Adrienne
core
Modification of the glycocalyx via ‘glycan editing’ is distinguishable from ‘glycan‐motif editing’. The former broadly remodels the glycocalyx, whereas the latter inhibits expression only of a specific oligosaccharide motif within the glycocalyx by selectively dampening the bioactivity of the key glycosyltransferase(s) programming the biosynthesis of ...
Barbara Richichi, Robert Sackstein
wiley +1 more source
In a cohort of central disorders of hypersomnolence, specifically women with idiopathic hypersomnia showed a marked subjective daytime sleepiness peak in the early 30s, while the body mass index only started to rise at that age. Better understanding of the pathophysiology of these gender and age‐specific characteristics will support tailored ...
Laura Ferrazzini +31 more
wiley +1 more source

