Philadelphia chromosome-positive (Ph+) leukemia is a fatal hematological malignancy. Although standard treatments with tyrosine kinase inhibitors (TKIs) have achieved remarkable success in prolonging patient survival, intolerance, relapse, and TKI ...
Mengya Zhao+10 more
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Labeling of v‐Src and BCR‐ABL tyrosine kinases with [14C]herbimycin A and its use in the elucidation of the kinase inactivation mechanism [PDF]
Hidesuke Fukazawa+5 more
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Induction of BCR‐ABL Fusion Genes by in vitro X‐irradiation [PDF]
Takashi Ito+7 more
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Failure to detect BCR-ABL message in some Ph+ hematopoietic colonies: methodological aspects of the reverse transcriptase-polymerase chain reaction assay [letter; comment] [PDF]
T Maekawa+4 more
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e8a2 BCR–ABL: more frequent than other atypical BCR–ABL variants? [PDF]
Giovanni Martinelli+13 more
openaire +3 more sources
BCR-ABL-mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: a mechanism of resistance to multiple anticancer agents [PDF]
A Bedi+8 more
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Bcr-Abl Exerts Its Antiapoptotic Effect Against Diverse Apoptotic Stimuli Through Blockage of Mitochondrial Release of Cytochrome C and Activation of Caspase-3 [PDF]
Gustavo P. Amarante‐Mendes+6 more
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Interaction of Abl Tyrosine Kinases with SOCS3 Impairs Its Suppressor Function in Tumorigenesis
Suppressor of cytokine signaling 3 (SOCS3) is involved in Bcr-Abl–induced tumorigenesis. However, how SOCS3 interacts with Bcr-Abl and is regulated by Abl kinases remains largely unknown.
Riyue Feng+8 more
doaj
BCR/ABL rearrangement and leukemia phenotype [PDF]
SAGLIO, Giuseppe+3 more
openaire +4 more sources
Kinetics of increasing BCR-ABL transcript numbers in chronic myeloid leukemia patients who relapse after bone marrow transplantation [PDF]
Feng Lin+3 more
openalex +1 more source