Results 91 to 100 of about 18,049 (264)

Electrostatically‐Stabilized PEG‐Free Lipid Nanoparticles for Systemic Nucleic Acid Delivery

open access: yesAdvanced Functional Materials, EarlyView.
This work describes non‐PEGylated layered lipid nanoparticles (nonPEG LLNPs), a gene delivery platform that improves upon standard PEGylated LNPs via electrostatic adsorption of charged polymers. nonPEG LLNPs maintain colloidal stability under biological stresses, enhance circulation time, and mitigate accelerated blood clearance and hepatic ...
Namita Nabar   +4 more
wiley   +1 more source

Tuning Mechanoreceptor Signaling Enhances the Adjuvant Effect of Biomaterial Vaccines

open access: yesAdvanced Functional Materials, EarlyView.
Matrix stiffness serves as an independent immunological signal in biomaterial vaccines. Stiffer microporous hydrogel vaccines enhance dendritic cell maturation and migration to draining lymph nodes, promote T follicular helper cell expansion through Yap/Taz signaling, and increase antigen‐specific antibody production.
Lily Shang   +13 more
wiley   +1 more source

Performance Assessment of Non-Integer-Hour Data Blocks in BDS Broadcast Ephemeris

open access: yesIEEE Access
Due to system anomalies, BeiDou navigation satellite system (BDS) sometimes updates the broadcast ephemeris at non-integral hours. The gross errors contained in the non-integer-hour data blocks of broadcast ephemeris will lead to the signal-in-space (SIS)
Jingjing Wang, Chao Zhou
doaj   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

Gellan Gum Fluid Gel System for Controlled‐Delivery of Cytokine‐Licensed MSC‐EVs to Enhance Corneal Repair in Limbal Stem Cell Deficiency

open access: yesAdvanced Healthcare Materials, EarlyView.
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh   +7 more
wiley   +1 more source

Use of the Behavioral Dyscontrol Scale-2 (BDS-2) to measure executive dysfunction in FXTAS

open access: yesFrontiers in Molecular Neuroscience
Background/objectiveFragile X-associated Tremor/Ataxia Syndrome (FXTAS) is a neurodegenerative disorder caused by a premutation (55 to 200 CGG repeats) in the FMR1 gene.
Seyedeh Ala Mokhtabad Amrei   +22 more
doaj   +1 more source

Correspondenz. [Bd.]2, 1803

open access: yes, 2014
http://www.ester.ee/record=b4043466~S1 ...
openaire   +1 more source

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