Results 41 to 50 of about 18,049 (264)

Analysis of BDS-3 Onboard Clocks Based on GFZ Precise Clock Products

open access: yesRemote Sensing, 2022
The characteristics and performance of satellite clocks are important to the positioning, navigation, and timing (PNT) services of Global Navigation Satellite System (GNSS) users.
Tao Geng, Rui Jiang, Yifei Lv, Xin Xie
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

A Comprehensive Signal Quality Assessment for BDS/Galileo/GPS Satellites and Signals

open access: yesRemote Sensing
With the modernization of global navigation satellite systems (GNSS), especially the rapid development of the BeiDou Navigation Satellite System (BDS), more observations of satellites and signals have become available.
Yijun Tian   +10 more
doaj   +1 more source

GPS/BDS-2/Galileo Precise Point Positioning Ambiguity Resolution Based on the Uncombined Model

open access: yesRemote Sensing, 2020
In this study, an uncombined precise point positioning (PPP) model was established and was used for estimating fractional cycle bias (FCB) products and for achieving ambiguity resolution (AR), using GPS, BDS-2, and Galileo raw observations.
Jin Wang   +5 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Characteristics of Inter-System Bias between BDS-2 and BDS-3 and Its Impact on BDS Orbit and Clock Solutions

open access: yesRemote Sensing, 2023
The inter-system-like bias between the regional (BDS-2) and global (BDS-3) constellation of the BeiDou Navigation Satellite System (BDS) has been identified on common B1I pseudo-range observations. In this study, its characteristics are investigated with
Xiaolong Xu, Zhan Cai
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Evaluating the accuracy of earth rotation parameters based on the BDS observations

open access: yesGeodesy and Geodynamics
The BeiDou satellite system (BDS) has progressed with the full operationalization of the second-generation regional system (BDS-2) and the third-generation global system (BDS-3).
Chenxiang Wang   +5 more
doaj   +1 more source

Precise Orbit and Clock Products of Galileo, BDS and QZSS from MGEX Since 2018: Comparison and PPP Validation

open access: yesRemote Sensing, 2020
In recent years, the development of new constellations including Galileo, BeiDou Navigation Satellite System (BDS) and Quasi-Zenith Satellite System (QZSS) have undergone dramatic changes. Since January 2018, about 30 satellites of the new constellations
Xingxing Li   +5 more
doaj   +1 more source

Assessing IGS GPS/Galileo/BDS-2/BDS-3 phase bias products with PRIDE PPP-AR

open access: yesSatellite Navigation, 2021
Ambiguity Resolution in Precise Point Positioning (PPP-AR) is important to achieving high-precision positioning in wide areas. The International GNSS (Global Navigation Satellite System) Service (IGS) and some other academic organizations have begun to ...
Jianghui Geng, Songfeng Yang, Jiang Guo
doaj   +1 more source

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