Results 231 to 240 of about 18,991 (299)

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Safety of oil from <i>Schizochytrium</i> sp. A2 for use in infant and follow-on formula as a novel food pursuant to regulation (EU) 2015/2283. [PDF]

EFSA J
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck D, Bohn T, Cámara M, Castenmiller J, De Henauw S, Jos Á, Maciuk A, Mangelsdorf I, McNulty B, Naska A, Pentieva K, Siani A, Thies F, Frenzel T, Aguilera-Gómez M, Marcon F, Neuhäuser-Berthold M, Nuin Garciarena I, Turla E, Favata A, Hirsch-Ernst KI.   +22 more
europepmc   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Factors associated with preterm birth and low birth weight among infants with congenital heart disease in Changsha City, China, 2022-2024. [PDF]

Sci Rep
Fu J, Liu J, Zhang B, Wang J, Wen Y, Fang J, Chen H.   +6 more
europepmc   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Oscillatory and behavioral indices of cognitive control dysregulation in young adult binge drinkers are influenced by sex differences. [PDF]

Alcohol Clin Exp Res (Hoboken)
Thomas VFU, Cruz SM, Huang S, Marinkovic K.   +3 more
europepmc   +1 more source

Surgical solution for retrograde peri-implantitis: A case report on managing implant-associated apical infection. [PDF]

Pak J Med Sci
Yaqoob H, Kazmi SMR, Khan SA, Sadiq A.
europepmc   +1 more source

Co-developing preoperative therapy for Dupuytren's fasciectomy: lived experience and clinical expertise. [PDF]

Res Involv Engagem
Babiker-Moore T, Schurer A, Hughes M, Clark CJ, Crook TB, Kavanagh E.   +5 more
europepmc   +1 more source

"No Words for Feelings": Alexithymia in Children With Cystic Fibrosis and Their Caregivers. [PDF]

Pediatr Pulmonol
Şişmanlar Eyüboğlu T, Aslan AT, Hocoğlu Zİ, Asfuroğlu P, Çakir EP, Soysal Acar AŞ, Medeni V.   +6 more
europepmc   +1 more source

Differential Accumulation Dynamics of Organic Matter in the Central and Eastern Bohai Bay Basin (Eastern China): Implications for Tectonic Activity. [PDF]

ACS Omega
Li Y, Chen Y, Ma Z, Pan K, Xu Y, Wu X, Zhang R, Song L, Ding Q, Qu L, Zhu Q.   +10 more
europepmc   +1 more source