Results 271 to 280 of about 19,364 (340)

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

CFP1-mediated H3K4me3 broad domains control early B cell lineage fate determination. [PDF]

Nucleic Acids Res
Bai W, Yang Y, Zhao Y, Gong S, Lu Y, Xue Z, Wang L, Meng FL, Chen C, Dong J.   +9 more
europepmc   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Wheat height monitoring from GPS/BDS reflected signals using pseudorange and dual-frequency carrier phase observables. [PDF]

Front Plant Sci
Sui M, Guan Z, Cui P.
europepmc   +1 more source

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Characteristics of Ionospheric Responses over China During the November 2023 Geomagnetic Storm and Evaluation of Positioning Performance of CORS in Low-Latitude Regions. [PDF]

Sensors (Basel)
Li L, Wang Y, Zhang J, Tang J, Yu F, Wang J, Zhang Z.   +6 more
europepmc   +1 more source

Synergistic Cardiopulmonary Protection of Endothelin Receptor Antagonists Combined With Soluble Guanylate Cyclase Agonists in High-Risk Coronary Syndrome With Pulmonary Hypertension. [PDF]

Rev Cardiovasc Med
Zhao L, Pang X.
europepmc   +1 more source

Effectiveness of COACH2COACH and R2C2 (Relationship, Reaction, Content, Coaching) Model in Improving Peer-feedback for students' professional development. [PDF]

Pak J Med Sci
Siddiqui S, Mahboob U, Shah S, Junaid SM.   +3 more
europepmc   +1 more source

Enhanced orbit determination for BDS-3 satellites with LEO onboard GNSS and inter-satellite link data

Hanlin Chen, Tao Geng, Xin Xie, Qiang Li, Xing Su, Qile Zhao   +5 more
openalex   +1 more source

The UK Standing Dental Advisory Committee (1948-2010) with special reference to its Expert Working Party on Orthodontics, 1992. [PDF]

Br Dent J
Stephens C.
europepmc   +1 more source