Results 41 to 50 of about 77,848 (283)

Band Distributions for Quantum Chaos on the Torus [PDF]

open access: yes, 1998
Band distributions (BDs) are introduced describing quantization in a toral phase space. A BD is the uniform average of an eigenstate phase-space probability distribution over a band of toral boundary conditions.
B. Simon   +30 more
core   +3 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Einleitung: Die IHRA-Arbeitsdefinition und die Diskussion um Begriffe und Definitionen von Antisemitismus [PDF]

open access: yesConflict & Communication Online, 2022
Die „Arbeitsdefinition Antisemitismus“ der „International Holocaust Remembrance Alliance“ führt nicht nur zu wissenschaftlichen Kontroversen zwischen ihren Befürworter:innen und Kritiker:innen, sie spielt – zumindest indirekt - auch für die Förderung ...
Florian Weis
doaj  

Chemical abundances of stars with brown-dwarf companions

open access: yes, 2014
It is well-known that stars with giant planets are on average more metal-rich than stars without giant planets, whereas stars with detected low-mass planets do not need to be metal-rich.
Hernández, J. I. González   +5 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Comparison of Pericapsular Nerve Group Block and Femoral Nerve Block for Ease of Positioning During Spinal Anaesthesia in Hip Fracture Surgeries: A Prospective Randomized Controlled Trial [PDF]

open access: yesĶazaķstannyṇ Klinikalyķ Medicinasy
Background: Hip fractures often require spinal anaesthesia for surgery, but positioning for spinal anaesthesia is painful, necessitating preoperative regional nerve blocks. This study compares ultrasound-guided pericapsular nerve group (PENG) and femoral
Tarun Yadav   +5 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

On the universal outcome of star-formation: Is there a link between stars and brown-dwarfs?

open access: yes, 2003
(abridged) The recent evidence obtained by Briceno et al. that star-formation in Taurus-Auriga (TA) may be producing significantly fewer brown dwarfs (BDs) per star than the ONC is investigated by setting up a realistic model stellar plus BD population ...
Aarseth   +82 more
core   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

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