Results 51 to 60 of about 72,789 (286)

The "Mysterious" Origin of Brown Dwarfs

, 2004
Hundreds of brown dwarfs (BDs) have been discovered in the last few years in stellar clusters and among field stars. BDs are almost as numerous as hydrogen burning stars and so a theory of star formation should also explain their origin.
Ake Nordlund, Baraffe I., Boldyrev S., Bonnor W., Bouvier J., Comeron F., D'Antona F., Jeans J., Larson R., Larson R., Larson R., McCrea W., Motte F., Paolo Padoan   +13 more
core   +5 more sources

New Black Hole Solutions in Brans-Dicke Theory of Gravity [PDF]

, 1999
Existence check of non-trivial, stationary axisymmetric black hole solutions in Brans-Dicke theory of gravity in different direction from those of Penrose, Thorne and Dykla, and Hawking is performed.
A.I. Janis, B.O.J. Tupper, C. Brans, C.B.G. McIntosh, D. Sudarsky, E.J. Newman, H.A. Buchdahl, Hongsu Kim, J.D. Bekenstein, J.D. Bekenstein, K.S. Thorne, R.A. Matzner, R.H. Boyer, R.M. Misra, R.N. Tiwari, R.N. Tiwari, R.P. Kerr, S. Weinberg, S.W. Hawking, T. Singh   +19 more
core   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Likelihood-Based Inference for Discretely Observed Birth-Death-Shift Processes, with Applications to Evolution of Mobile Genetic Elements

, 2014
Continuous-time birth-death-shift (BDS) processes are frequently used in stochastic modeling, with many applications in ecology and epidemiology. In particular, such processes can model evolutionary dynamics of transposable elements - important genetic ...
Biémont, Catlin, Cattamanchi, Crawford, Crawford, Dempster, Doss, Gagneux, Golinelli, Henrici, Huber, Kato-Maeda, Keiding, Lange, McEvoy, Minin, Rosenberg, Schwarz, Tanaka, Van Embden   +19 more
core   +1 more source

Band Distributions for Quantum Chaos on the Torus [PDF]

, 1998
Band distributions (BDs) are introduced describing quantization in a toral phase space. A BD is the uniform average of an eigenstate phase-space probability distribution over a band of toral boundary conditions.
B. Simon, D. J. Thouless, D. P. Arovas, F. Faure, F. Faure, G. Junker, H. Primack, I. Dana, I. Dana, I. Dana, I. Dana, I. Dana, Itzhack Dana, J. E. Avron, J. H. Hannay, J. P. Keating, M. V. Berry, M. V. Berry, M. Wilkinson, M. Wilkinson, M. Wilkinson, Mario Feingold, Michael Wilkinson, P. Leboeuf, P. Leboeuf, P. Leboeuf, P. Leboeuf, P. N. Walker, R. Artuso, R. Roncaglia, Ya. G. Sinai   +30 more
core   +3 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Brown dwarf formation by gravitational fragmentation of massive, extended protostellar discs

, 2007
We suggest that low-mass hydrogen-burning stars like the Sun should sometimes form with massive extended discs; and we show, by means of radiation hydrodynamic simulations, that the outer parts of such discs (R>100 AU) are likely to fragment on a ...
Hubber, David, Stamatellos, Dimitris, Whitworth, Anthony   +2 more
core   +2 more sources

Analysis of BDS/GPS Signals’ Characteristics and Navigation Accuracy for a Geostationary Satellite [PDF]

, 2021
Meng Wang, Tao Shan, Wanwei Zhang, Hao Huan   +3 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Chemical tracers in proto-brown dwarfs: CN, HCN, and HNC observations

, 2018
We present results from a study of nitrogen chemistry in Class 0/I proto-brown dwarfs (proto-BDs). We have used the IRAM 30 m telescope to observe the CN (2-1), HCN (3-2), and HNC (3-2) lines in 7 proto-BDs.
Caselli, P., Riaz, B., Thi, W. -F.
core   +1 more source