Results 81 to 90 of about 34,202 (311)
, 2023 Supplemental material, sj-docx-1-bds-10.1177_20539517231205479 for ‘Blockchain for good’: Exploring the notion of social good inside the blockchain scene by Silvia Semenzin in Big Data ...
Silvia Semenzin (17179945)
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
, 2018 Many important cloud services require replicating massive data from one datacenter (DC) to multiple DCs. While the performance of pair-wise inter-DC data transfers has been much improved, prior solutions are insufficient to optimize bulk-data multicast ...
Junchen Jiang +17 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
, 2023 Supplemental material, sj-csv-1-bds-10.1177_20539517231171052 for FAIR data sharing: An international perspective on why medical researchers are lagging behind by Linda Rainey, Jennifer E Lutomski and Mireille JM Broeders in Big Data ...
Jennifer E Lutomski (15417510) +2 more
core +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Assessment of BeiDou-3 and Multi-GNSS Precise Point Positioning Performance
Sensors, 2019 With the launch of BDS-3 and Galileo new satellites, the BeiDou navigation satellite system (BDS) has developed from the regional to global system, and the Galileo constellation will consist of 26 satellites in space. Thus, BDS, GPS, GLONASS, and Galileo
Guoqiang Jiao +4 more
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source